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NCT ID: NCT04597996 Not yet recruiting - Clinical trials for Mental Health Literacy

Web-based Mental Health Literacy Program

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Mental health literacy is a concept that aims to improve the skills of individuals to overcome difficulties in providing the appropriate help they need in this area. It provides individuals with motivation in this area such as informing and taking responsibility in the field of mental health, directing their behavior, facilitating access to and obtaining information, understanding, evaluating, using, and maintaining information. Objective: This project aims to examine the effect of web-based mental health literacy intervention carried out by school nurses on students' level of knowledge, help-seeking and stigmatization attitudes. Method: Randomized Controlled Trial Research design (pre-test post-test control group design) will be used in the project. The data will be collected through the Mental Health Literacy Scale for Children and Adolescents (MHLS), Attitude Scale for Seeking Psychological Help-Short Form (ASPH-S), Self-Stigma in Seeking Psychological Help Scale (SSSPHS) and the sociodemographic Question Form. The project will be carried out with the students of a secondary school and a high school in the district of Balçova, İzmir province. Sampling calculation Based on the analysis of variance in repeated measurements in 2 groups in the G Power program, Type1 Error 0.05 (alpha 5%) Type2 Error 0.20 (80% power), the sample size calculated in duplicate measurements with medium effect size is 43 participants for each group (Intervention-Control) calculated. Considering that there might be losses during data collection, it is planned to include 50 students for the intervention group and 50 students for the control group. Analysis of variance will be used in the evaluation of data, number, percentage, and descriptive statistics, and in repeated measures to evaluate the effect of the intervention The training modules to be prepared within the scope of the project will focus on the mental health literacy level of the child, attitudes to seek help and stigmatization. Among the teaching materials planned to be prepared for this purpose, there will be short animated course videos, video course contents, and audio presentations. In the study, where web-based education is planned, teaching materials will be delivered to students through the learning management system. Teaching materials and learning management systems will be designed in accordance with mobile technologies and access will be provided from smartphones, tablet computers, and similar mobile devices. During the teaching material development phase, firstly, educational content drafts (storyboards) will be created and presented to field experts, and their opinions on content, teaching approach, methods and techniques, and visual design principles will be taken. Pilot studies will be conducted to understand the educational content during the improvement phase of the developed teaching material designs. It is planned to finalize the training content in light of user feedback.

NCT ID: NCT04814394 Not yet recruiting - Clinical trials for Autoimmune Hemolytic Anemia

The Significance of Release of T-follicular Helper and T-follicular Regulatory Cells in Autoimmune Haemolytic Anemia Before and After Tratment

fhfr
Start date: April 1, 2022
Phase:
Study type: Observational

we study the circulating T-follicular regulatory and T-follicular regulatory cells in autoimmune hemolytic anemia.

NCT ID: NCT04815629 Not yet recruiting - Clinical trials for Urinary Bladder Squamous Cell Carcinoma

Outcome of Radiation Therapy in Urinary Bladder Squampus Cell Carcinoma

Start date: April 1, 2022
Phase:
Study type: Observational

Detection of distribution of clinico-pathological features of squamous cell carcinoma of urinary bladder and their relation to treatment outcome.

NCT ID: NCT04829942 Not yet recruiting - Health Literacy Clinical Trials

Evaluation of the Effectiveness of "School Health Nursing Program" Implemented Under the Leadership of Nurse

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

It is very important for children to take their own health responsibilities in giving them positive health behavior. The rapid advancement of technology, cultural differences, changing living conditions, and increasing chronic diseases show us that people should have the authority to make decisions about their own health, starting from primary school and childhood. All these bring the concept of health literacy to the fore. According to WHO, the concept of health literacy is the cognitive and social skills about individuals' ability to access, understand and use information and their desires in order to protect and improve well-being in health. Providing appropriate health education for age groups is very important for the development of health literacy in children. School-based health education is necessary for health promotion in the 21st century. Studies show that children's health literacy levels are low. There are very few scales that measure health literacy in children. Although there are no school health nursing practices in Northern Cyprus, there are no training programs to develop positive health behaviors. With this study we have planned, it is aimed to implement a training program within the scope of the "School Health Nursing Program" in primary schools selected as a pilot in Northern Cyprus and to form the foundations of School health nursing in our country in line with its results. In addition, measurement tools specific to age groups are needed to measure the level of health literacy, especially in school-age children. Therefore, another purpose of this study is to evaluate the effectiveness of this program on children by implementing an education program within the scope of the "School Health Nursing Program", which will be a first in our country, and to develop the "Child Health Literacy Scale" and to make it a significant contribution to science with this scale.

NCT ID: NCT04855526 Not yet recruiting - Cannabis Use Clinical Trials

THC + CBD and Memory Study

Start date: April 1, 2022
Phase: Early Phase 1
Study type: Interventional

Memory deficits are one of the most consistently observed cognitive effects of marijuana use. There is evidence that some decrements attributable to the primary psychoactive ingredient, delta-9-tetrahydrocannabinol (THC), may be attenuated by cannabidiol (CBD). This study will help us learn more about the relationship between THC and CBD consumption with memory processes. A combination of MRI and neuropsychological tests (which are computer and paper/pencil tasks) will be used to measure the neurocognitive and behavioral impacts of THC and CBD use.

NCT ID: NCT04968444 Not yet recruiting - Back Pain Clinical Trials

BOOST Workshop Versus Traditional 1-1 Physiotherapy for Back Pain

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

This research is aiming to address whether a group workshop is a more superior treatment to traditional physiotherapy for the management of back pain in a hospital workforce. In the UK during 2016-17, 31.2 million work days were lost due to work-related ill health and injury. Of these 8.9 million were down to musculoskeletal disorders. This equated to 17.6 days per person. In the general population, the reports of low back pain have been as high as 36% of adults with a first occurrence. In an adult's lifetime, the prevalence of chronic low back pain is about 23%. This makes the importance of managing these conditions of great importance. And the impact to a working population is great, in respects to work satisfaction, sickness and absenteeism. Significance should also be placed on the impact this has to the individual, with regards to their health and wellbeing. The participants will be taken from NHS staff working within the hospital environment and that self-refer internally for physiotherapy into the Trust's Occupational Health Service. Once the participants are accepted in Occupational Health Physiotherapy, they are managed as staff requiring physiotherapy and not at 'patients'. There is no contact with their primary care practitioner. For the study, participants will either receive traditional one to one physiotherapy or a bespoke one off workshop. All of the participants will be followed up 3 months after their treatment has finished.

NCT ID: NCT04974138 Not yet recruiting - Hypertension Clinical Trials

China Stroke Primary Prevention Trial for Subjects With H-type Hypertension and MTHFR 677 CC/CT Genotype

CSPPT2-CC/CT
Start date: April 1, 2022
Phase: Phase 4
Study type: Interventional

This is a multicenter, randomized, controlled, clinical trial stratified by participants with the MTHFR 677 genotype (CC and CT) in a 1:1 ratio. It aims to investigate the treatment effects of amlodipine folic acid vs. amlodipine on reducing the risk of first ischemic stroke among those participants with the MTHFR 677 CC/CT genotype and H-type hypertension (hypertension with increasing homocysteine (Hcy)). This study consists of 3 phases: Screening, Run-in period (0 or 2 weeks), and randomized treatment (5 years), with a prospective, randomized, open-label, blinded end-point design.

NCT ID: NCT04974151 Not yet recruiting - Hypertension Clinical Trials

China Stroke Primary Prevention Trial for Subjects With Hypertension and MTHFR 677 TT Genotype (CSPPT2-TT)

CSPPT2-TT
Start date: April 1, 2022
Phase: Phase 4
Study type: Interventional

This is a multicenter, randomized, controlled clinical trial. It aims to investigate the treatment effects of amlodipine folic acid, and its combination of 5-methyltetrahydrofolate (5-MTHF), compared to amlodipine, on reducing the risk of first ischemic stroke among those participants with the MTHFR 677 TT genotype and hypertension. This study consists of 3 phases: Screening, Run-in period (0 or 2 weeks), and randomized treatment (5 years), with a prospective, randomized, open-label, blinded end-point design.

NCT ID: NCT05057624 Not yet recruiting - Clinical trials for Posttraumatic Stress Disorder

Gaze-Contingent Music Reward Treatment for PTSD

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The present study is a double-blind trial that seeks to examine the feasibility, acceptability, and efficacy of a recently developed eye-tracking-based, gaze-contingent music reward therapy (GC-MRT) in individuals with posttraumatic stress disorder (PTSD). The specific aims of this study are to: (1) examine the efficacy of GC-MRT in PTSD; and (2) elucidate its underpinnings (i.e. attention control, reward processes, and exposure via counter-conditioning). The investigators hypothesize that: 1. GC-MRT will produce greater reductions in symptoms compared to PC at post-treatment and follow-up (diverting attention away from threat). 2. GC-MRT-exp will produce greater reductions in symptoms compared to PC at post-treatment follow-up (exposure via counter-conditioning by rewarding threat stimuli). 3. Exploratory analysis will compare the reductions in symptoms of GC-MRT compared to GC-MRT-exp at post-treatment follow-up.

NCT ID: NCT05078125 Not yet recruiting - Clinical trials for Premature Ventricular Complex

Electrocardiographic and Cardiac Magnetic Resonance Predictors of Ventricular Arrhythmias in Cardiomyopathic Patients

Start date: April 1, 2022
Phase:
Study type: Observational

This study aims to assess ECG changes for predicting ventricular arrhythmia in cardiomyopathic patients