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NCT ID: NCT05002465 No longer available - Prostate Cancer Clinical Trials

Clinical Use of 68Ga PSMA-11 PET/CT in Diagnosing, Staging and Restaging Prostate Cancer

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this protocol is to provide 68Ga Prostate Specific Membrane Antigen-11 (68Ga PSMA-11) for clinical use in the diagnosis, staging and restaging of prostate cancer using Positron Emission Tomography with Computed Tomography (PET/CT) prior to its full local Federal Drug Administration (FDA) approval. Extensive research has shown that 68Ga PSMA-11 PET/CT offers higher detection rate of metastatic disease in prostate cancer than the current standard of care usually used in staging and restaging prostate cancer.

NCT ID: NCT05014724 No longer available - Clinical trials for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

CIDP07 Rozanolixizumab Post Trial Access Program (the PTA)

Start date: n/a
Phase:
Study type: Expanded Access

This Post Trial Access (PTA) Program enables access to rozanolixizumab for eligible patients who have taken part in the CIDP04 trial (NCT04051944) and are continuing to derive benefit from treatment.

NCT ID: NCT05086094 No longer available - Clinical trials for Multiple System Atrophy (MSA)

Expanded Access Protocol of Verdiperstat in Patients With Multiple System Atrophy (MSA)

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this expanded access program is to provide access to the investigational drug verdiperstat in patients with Multiple System Atrophy (MSA). Expanded access allows patients with a serious or a life-threatening disease or condition access to an investigational drug when no satisfactory approved treatment options are available.

NCT ID: NCT05107193 No longer available - Solid Tumors Clinical Trials

Afatinib (GILOTRIF®) in Patients Suffering From Tumors Harboring Neuregulin 1 (NRG1) Gene Alterations (Specifically NRG1 Gene Fusion-positive Advanced Solid Tumors)

Start date: n/a
Phase:
Study type: Expanded Access

Gene fusions are defined as two separate genes joined together (gene 1, gene 2), generating a novel fusion gene. NRG1 fusions are rare and complex with regard to the fusion/fusion partner. The specific NRG1 gene fusion will be identified by a specialized molecular testing lab.

NCT ID: NCT05108740 No longer available - Clinical trials for Advanced Hormone Receptor Positive (HR+) Breast Cancer

MAP Treatment Plan With Afinitor for Postmenopausal Women With Advanced HR+ Breast Cancer

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this Managed Access Program (MAP) Cohort Treatment Plan is to provide guidance to the Physician for the treatment and monitoring of patients in the Cohort MAP.

NCT ID: NCT05124990 No longer available - Clinical trials for Rheumatoid Arthritis

Predictive Clinical Diagnosis of Rheumatoid Arthritis Flares Using Non-Invasive Infra-red Thermal Imaging and an AI/ML Algorithm

Start date: n/a
Phase:
Study type: Expanded Access

The hypothesis for this clinical research project is that the severity of RA may be detected and predicted using an optimized ML/AI algorithm that uses infrared thermal images of inflamed joints and standard clinical RA-related markers (i.e., ESR and CRP) by computing DAS-28 ESR scores in real-time. The infrared thermal images coupled with clinical laboratory markers and the ML/AI algorithm are expected to assist a practicing clinician in the RA diagnosis and the prediction of the occurrence of flares in RA patients. Physicians who use this technology, would need minimum training and will be able to accurately and reliably diagnose RA using a cheaper method which does not involve incident radiation emitted by other imaging modalities such a X-RAY, musculoskeletal (MSK) ultrasound, or a magnetic resonance imaging (MRI). The aim would be to have the Infrared thermal imaging devices at remote VA clinics that do not have a rheumatology specialist where veterans can go for their inflammatory arthritis flare and get this image by the local VA RN. These clinical results can then be assessed by and discussed with a Rheumatologist via telehealth visits.

NCT ID: NCT05131438 No longer available - Clinical trials for Extranodal NK/T-cell Lymphoma

An Expanded Access Program to Provide Sugemalimab for the Treatment of Relapsed or Refractory Extranodal Natural Killer/T-Cell Lymphoma (R/R ENKTL)

Start date: n/a
Phase:
Study type: Expanded Access

This program is intended to provide access to sugemalimab for participants with R/R ENKTL, after their disease failed to respond to prior treatment regimen(s), preceding marketing authorization by the local regulatory agency.

NCT ID: NCT05154851 No longer available - Clinical trials for Congenital Muscular Dystrophy Due to Lamin A/C Mutation

HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy.

Start date: n/a
Phase:
Study type: Expanded Access

This individual patient expanded access IND is requested for a patient diagnosed with LMNA-related congenital muscular dystrophy (L-CMD). In this expanded access, the patient will receive the investigational product through 14 intravenous infusions, followed by Follow-Up visit and an End of Study.

NCT ID: NCT05157165 No longer available - COVID-19 Clinical Trials

Convalescent Plasma in Hospitalized COVID-19 Patients

Start date: n/a
Phase:
Study type: Expanded Access

The study assesses the efficacy and safety of administration of hyperimmune plasma in hospitalized COVID-19 patients. Efficacy was measured as 28-day mortality following convalescent plasma transfusion. Safety was measured as the rate of adverse reactions. to plasma infusion.

NCT ID: NCT05161598 No longer available - Multiple Myeloma Clinical Trials

Pre-approval Access Single Patient Request for Teclistamab (JNJ-64007957)

Start date: n/a
Phase:
Study type: Expanded Access

Teclistamab pre-approval access in relapsed or refractory multiple myeloma.