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NCT ID: NCT06355544 Not yet recruiting - Healthy Clinical Trials

Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk

PINEAPPL
Start date: April 2024
Phase:
Study type: Observational

The goal of this observational study is to learn about low-grade inflammation in healthy individuals and individuals with overweight or obesity. The main questions it aims to answer are: - Whether it is possible to predict low-grade inflammation - What are the medical, biological, and lifestyle variables related to low-grade inflammation? Participants will be asked to: 1. Attend a general medical visit to collect vital signs, anthropometric measurements, and collect blood samples. 2. Complete questionnaires and collect a stool sample at home.

NCT ID: NCT06355687 Not yet recruiting - Anesthesia Clinical Trials

Melatonin in Obese Patients in Laparoscopic Cholecystectomy

Start date: April 2024
Phase: N/A
Study type: Interventional

Opioid free anesthesia (OFA) means a technique in which no intraoperative opioid is administered through any route. Perioperative pain management in an obese patient is challenging. The incidence of respiratory depression is higher in obese patients and is exaggerated with opioids, so the investigators are searching for a drug that has analgesic effect without any effect on respiratory function. In this study, the investigators will add melatonin to OFA in obese patients undergoing laparoscopic cholecystectomy.

NCT ID: NCT06355778 Not yet recruiting - Healthy Clinical Trials

Adversity, Brain and Opioid Use Study

Start date: April 2024
Phase: N/A
Study type: Interventional

The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms. The purpose of this project is to examine brain function and performance during learning and memory tasks in adults. The study will compare measures of learning and memory across three groups of participants: those with an Opioid Use Disorder (OUD) that take buprenorphine for opioid replacement therapy, adults without an Opioid Use Disorder taking buprenorphine, and healthy adults that do not have an Opioid Use Disorder and are not taking buprenorphine.

NCT ID: NCT06355856 Not yet recruiting - Alopecia Clinical Trials

Efficacy/ Safety of DNN.22.17.036 in Male Patients With Pattern Hair Loss

CAPELLI
Start date: April 2024
Phase: Phase 4
Study type: Interventional

Evaluation of the efficacy and safety of DNN.22.17.036 versus 10573048700 in the treatment of male pattern hair loss.

NCT ID: NCT06355895 Not yet recruiting - Clinical trials for Upper Abdominal Malignancies

Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies

Start date: April 2024
Phase: N/A
Study type: Interventional

Standard planning constraints for liver SBRT incorporate strict dose-volume limits for normal liver parenchyma to minimize the risk of radiation-induced liver disease. The presence of diurnal and fasting/fed variations in liver volume therefore carry substantial potential for introducing errors into estimates of dose-volume distribution within normal liver tissue, as well as affecting day-to-day setup fidelity and organ alignment for treatment. This prospective study will examine how diurnal and fast-fed variations in liver volume affect treatment planning for abdominal SBRT.

NCT ID: NCT06355973 Not yet recruiting - Clinical trials for Patients With Mild Cognitive Impairment (MCI)

A Pilot Study for Efficacy of Cognitive and Physical Training in Patients With Mild Cognitive Impairment

Start date: April 2024
Phase: N/A
Study type: Interventional

This is to find out the effectiveness of cognitive and physical function training for patients with mild cognitive impairment. It is for the prevention and treatment of dementia in the future. randomized, Pilot Study.

NCT ID: NCT06356441 Not yet recruiting - Clinical trials for Artificial Intelligence Supported Image Reviewing

Artificial Intelligence-supported Reading Versus Standard Double Reading for the Interpretation of Magnetic Resonance Imaging in the Detection of Local Recurrence for Nasopharyngeal Carcinoma: a Randomised Controlled Multicenter Study

Start date: April 2024
Phase:
Study type: Observational

The aim of this randomized controlled study is to investigate whether the previously developed artificial intelligence model can triage post-radiotherapy magnetic resonance images of patients with nasopharyngeal carcinoma and assist radiologists in their interpretation.

NCT ID: NCT06356545 Not yet recruiting - Diarrhea Infantile Clinical Trials

Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China

Start date: April 2024
Phase:
Study type: Observational

This study will establish a clinical cohort of children with congenital diarrhea and enteropathy (CODE), mine biomarkers of CODE through multi-omics technology and construct a clinical risk prediction model.

NCT ID: NCT06356857 Not yet recruiting - Clinical trials for Myocardial Blood Flow

Assessing Repeatability and Intra-individual Variability in [O15]H2O-PET Myocardial Perfusion Imaging

Heart-Wave
Start date: April 2024
Phase:
Study type: Observational

This study wish to assess the reproducibility of baseline and hyperemic myocardial blood flow as well as myocardial blood flow reserve measurements with [O15]H2O-PET-MPI.

NCT ID: NCT06357442 Not yet recruiting - Clinical trials for Hypogonadotropic Hypogonadism

Assessment of Endometrial Thickness Among Adolescent and Young Adult Patients on Estrogen Replacement Therapy Using Daily Oral Micronized Progesterone Versus the Etonogestrel Implant.

Start date: April 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to compare endometrial stripe thickness in adolescent and young adult (AYA) patients with a uterus on estrogen replacement therapy using oral progesterone versus the etonogstrel implant for endometrial protection. The main questions it aims to answer are: Aim 1: Characterize the mean endometrial thickness in AYA on estrogen hormone replacement therapy before initiation of progesterone therapy Aim 2: Characterize the mean changes and variability in endometrial thickness in AYA treated for 6 months with either the etonogestrel implant or continuous oral progesterone Aim 3: Assess satisfaction, side effects, bleeding patterns, any progesterone modifications, and adherence in AYA treated for 6 months with either etonogestrel implant or continuous progesterone Participants will be asked to: - Get two pelvic ultrasounds - Fill out two surveys - Continue their current hormone replacement therapy - Initiate one of two progesterone therapies (prometrium 100mg daily or Nexplanon) Researchers will compare the change in endometrial thickness after 6 months of progesterone use to see if there is a significant difference in the mean change between the prometrium and Nexplanon groups.