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NCT ID: NCT04777916 Recruiting - Clinical trials for Acute Myeloid Leukemia (AML)

Prospective Non-interventional Study of Adult Patients With Acute Myeloid Leukemia (AML)

ALFAPPP
Start date: April 14, 2022
Phase:
Study type: Observational [Patient Registry]

During the last fifteen years, the landscape of AML diagnosis and therapeutical options has markedly evolved. Refined genetic and prognostic characterizations, together with new drug approvals and new allogeneic hematopoietic stem cell transplantation (HSCT) procedures, have increased patient journey diversity.

NCT ID: NCT04783857 Recruiting - Smoking Cessation Clinical Trials

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

Start date: April 14, 2022
Phase: Phase 4
Study type: Interventional

The investigators aim to address the following specific aims: - Determine the efficacy of Prog in preventing postpartum smoking relapse and reducing smoking relapse risk factors. - Examine the effects of this maternal smoking intervention on infant health. - Examine racial and ethnic differences in intervention outcomes.

NCT ID: NCT04847089 Recruiting - Stroke Clinical Trials

Motor Imagery BCI Rehabilitation After Stroke

Start date: April 14, 2022
Phase: N/A
Study type: Interventional

This research project will investigate motor imagery training in stroke rehabilitation during which patients receive feedback in real time from their brain activity measured with ElectroEncephaloGraphy (EEG). The investigators hypothesize that the feedback training allows to internally stimulate brain motor networks in order to promote functional recovery of the hand.

NCT ID: NCT04978428 Recruiting - Clinical trials for Obsessive-Compulsive Disorder

Epidiolex in Obsessive Compulsive Disorder and Related Disorders

Start date: April 14, 2022
Phase: Phase 2
Study type: Interventional

The primary objective of the proposed study is to evaluate the safety and efficacy of Epidiolex (cannabidiol) in adults with obsessive compulsive and related disorders (OCRDs). Subjects will be treated in an open-label fashion with Epidiolex for two weeks.

NCT ID: NCT05023096 Recruiting - Clinical trials for Electronic Nicotine Delivery System Flavors

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

RVA Flavors
Start date: April 14, 2022
Phase: N/A
Study type: Interventional

This study aims to better understand how the availability of electronic nicotine delivery system (aka electronic cigarettes) flavors (e.g., menthol, tobacco) impacts tobacco use behaviors, toxicant exposure, and abuse liability among African American menthol smokers.

NCT ID: NCT05061550 Recruiting - Clinical trials for Non-small Cell Lung Cancer

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

NeoCOAST-2
Start date: April 14, 2022
Phase: Phase 2
Study type: Interventional

The study is intended to assess the safety and efficacy of perioperative treatment with Durvalumab in combination with Oleclumab, Monalizumab or AZD0171 and platinum doublet chemotherapy (CTX); or Volrustomig in combination with platinum doublet chemotherapy or datopotamab deruxtecan (Dato-DXd) in combination with durvalumab and single agent platinum chemotherapy in participants with resectable, early-stage non-small cell lung cancer.

NCT ID: NCT05070247 Recruiting - Breast Cancer Clinical Trials

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

Start date: April 14, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This study is about TAK-500, given either alone or with pembrolizumab, in adults with select locally advanced or metastatic solid tumors. The aims of the study are: - to assess the safety profile of TAK-500 when given alone and when given with pembrolizumab. - to assess the anti-tumor effects of TAK-500, when given alone and when given with pembrolizumab, in adults with locally advanced or metastatic solid tumors. Participants may receive TAK-500 for up to 1 year. Participants may continue with their treatment if they have continuing benefit and if this is approved by their study doctor. Participants who are receiving TAK-500 either alone or with pembrolizumab will continue with their treatment until their disease progresses or until they or their study doctor decide they should stop this treatment.

NCT ID: NCT05137873 Recruiting - Clinical trials for Great Vessels Transposition Surgery

Measurement of the Prevalence of Sensory Integration Disorders in Babies Having Heart Disease Surgery for Transposition of the Great Vessels Before 6 Months of Age

SENSOCOEUR
Start date: April 14, 2022
Phase:
Study type: Observational

The purpose of this study is to mesure the prevalence of severe sensory integration disorders in babies after one week of their heart surgery.

NCT ID: NCT05167344 Recruiting - Adolescent Behavior Clinical Trials

Evaluation of the Healthy Relationships Program-Enhanced (HRP-E) for Vulnerable Youth

HRP-E
Start date: April 14, 2022
Phase: N/A
Study type: Interventional

Investigators will work with community partners to undertake an evaluation of the impact of the Healthy Relationships Program-Enhanced (HRP-E) for youth to build evidence on effective programming with diverse vulnerable youth populations in real-world contexts. Youth participants will complete four surveys before and after participating in the HRP-E program and an interview approximately 4 to 6 months after participating in the program. Program facilitators will also track session activities and youth participation throughout the program and are invited to participate in a survey after the program is complete.

NCT ID: NCT05177458 Recruiting - PTSD Clinical Trials

Exercise and Therapeutic Exposure

Start date: April 14, 2022
Phase: N/A
Study type: Interventional

The proposed project seeks to demonstrate that a brief bout of aerobic exercise can improve a particular type of therapeutic learning among victimins of interpersonal violence with or without posttraumatic stress disorder (PTSD).