Breast Neoplasm Female Clinical Trial
Official title:
Peking University Cancer Hospital & Institute
This study investigates the efficacy and safety of trastuzumab, pyrotinib combined with dalpiciclib and endocrine therapy for patients with advanced HR+/HER2+ brest cancer, providing more possible effective regimens for the survival benefit of these patients in clinical practice.
This study is a single-arm, open-label, multicenter, phase II clinical study. Subjects were eligible for screening and entered the trial period after enrollment and received treatment with pyrotinib（320mg/day), trastuzumab(8 mg→6mg/every 3 week), dalpiciclib(125mg once daily for 3 weeks, followed by 1 week off in each 4-week cycle), endocrine therapy until disease progression, or intolerable toxicity, or withdrawal of informed consent, or discontinuation of medication at the investigator 's discretion. On-study imaging assessments were performed according to RECIST 1.1 criteria and the site assessment was final. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03980626 -
Study on Physical Activity's Relationship With Cancer and Cognition
|
N/A | |
| Completed |
NCT04329819 -
Satisfaction and QUality of Life After Breast REconstruction
|
||
| Recruiting |
NCT03323346 -
Phase II Trial of Disulfiram With Copper in Metastatic Breast Cancer
|
Phase 2 | |
| Active, not recruiting |
NCT03900884 -
Palbociclib, Letrozole & Venetoclax in ER and BCL-2 Positive Breast Cancer
|
Phase 1 | |
| Completed |
NCT05042999 -
The Use of Virtual Reality During Breast Ultrasound-Guided Biopsy Procedures
|
N/A | |
| Not yet recruiting |
NCT03662633 -
Diagnosis Value of SEMA4C in Breast Cancer
|
||
| Recruiting |
NCT05075512 -
The Efficacy and Safety of Anlotinib Combined With Fulvestrant in Patients With Advanced Breast Cancer
|
Phase 2 | |
| Recruiting |
NCT04456855 -
Locoregional Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer Patients
|
||
| Not yet recruiting |
NCT03629509 -
BEFORE Decision Aid Implementation Study
|
N/A | |
| Completed |
NCT04811378 -
HaemoCerTM Application in Breast Cancer Surgery
|
N/A | |
| Completed |
NCT03198442 -
Breast PET Feasibility
|
N/A | |
| Enrolling by invitation |
NCT04047823 -
Temperature and Injury in Radiotherapy Radiation Skin Injury
|
||
| Recruiting |
NCT05452213 -
Comprehensive Analysis of Spatial, Temporal and Molecular Patterns of Ribociclib Efficacy and Resistance in Advanced Breast Cancer Patients
|
Phase 4 | |
| Recruiting |
NCT05027321 -
Efficacy of Preparation in Self-Hypnosis by Anchoring Versus Conversational Hypnosis, Used Alone or Combined, in Patients Undergoing Breast Macrobiopsies
|
N/A | |
| Active, not recruiting |
NCT04812652 -
Digitally Distributed Yoga for Women Treated for Breast Cancer
|
N/A | |
| Active, not recruiting |
NCT03425838 -
Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer
|
Phase 3 | |
| Completed |
NCT05473026 -
Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors
|
N/A | |
| Completed |
NCT04509063 -
Investigating Public Enthusiasm for Mammography Screening in Denmark
|
N/A | |
| Recruiting |
NCT05711030 -
Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery
|
N/A | |
| Suspended |
NCT03271853 -
Thermalogical Analysis of a Cohort of Women and Men Undergoing Mammographic Analysis.
|
N/A |