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Clinical Trial Summary

This clinical trial will enroll subjects with HER2+ solid tumors and is conducted in two phases, which are phase 1a and phase 1b. The primary objective of phase 1 is to determine the safety and tolerability of AB-201 in subjects with advanced HER2+ solid tumors.


Clinical Trial Description

This is a Phase 1, multicenter study designed to evaluate the safety, tolerability, and efficacy of AB-201 in subjects with advanced HER2+ solid tumors (specifically, breast and gastric/GEJ cancers). The Phase 1 will be conducted in two parts, an initial dose escalation stage followed by a dose expansion stage. Study participation for each subject begins with up to 28 days (1 month) of screening following written informed consent, then lymphodepletion treatment, followed by AB-201. Up to 3 doses of AB-201 may be administered. All subjects will be monitored for a total duration of 18 months of follow up from the first dose administration of AB-201. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06341647
Study type Interventional
Source GC Cell Corporation
Contact HyeSung Jeon
Phone +82-31-260-9059
Email hs_jeon@gccorp.com
Status Not yet recruiting
Phase Phase 1
Start date August 31, 2024
Completion date February 2029

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