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DV in Combination With Pertuzumab With or Without Toripalimab Neoadjuvant Therapy With HER2-positive Breast Cancer

Breast Cancer Clinical Trial

Official title:
A Phase II, Multicenter, Open-Label Neoadjuvant Study to Evaluate the Safety and Efficacy of Disitamab Vedotin in Combination With Pertuzumab With or Without Toripalimab for HER2 Positive Breast Cancer

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of Disitamab Vedotin in combination with Pertuzumab with or without Toripalimab neoadjuvant therapy in patients with HER2-positive breast cancer.

Clinical Trial Description

This is an open-label, randomized, multicenter, Phase II Study designed to evaluate safety and efficacy of Disitamab Vedotin in combination with Pertuzumab with or without Toripalimab neoadjuvant therapy inr patients with HER2-positive breast cancer. The primary objectives of the study are to explore combination neoadjuvant therapy in participants with previously untreated HER2-positive breast cancer, by assessment of pCR . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06178159
Study type Interventional
Source RemeGen Co., Ltd.
Contact Jianmin Fang, Ph.D
Phone +8610-58075763
Email Jianminfang@hotmail.com
Status Recruiting
Phase Phase 2
Start date November 28, 2023
Completion date June 2025
View Details
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