Clinical Trials Logo

Clinical Trial Summary

For patients with HER2-positive early-stage breast cancer, NCCN guidelines recommend chemotherapy plus targeted therapy as the standard adjuvant treatment for patients with tumors larger than 1 cm or lymph node-positive. The APT study enrolled patients with stage I HER2-positive breast cancer and has confirmed the efficacy and safety of intravenous chemotherapy combined with targeted therapy, but only 2.2% of the patients enrolled in microinvasion are enrolled, and there is a lack of large sample size data to provide a treatment reference for these patients. In order to further explore the optimal strategy for adjuvant therapy in this type of patient, we designed a new clinical trial to evaluate the efficacy and safety of oral capecitabine plus pyrotinib as adjuvant therapy in previous retrospective studies.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05861271
Study type Interventional
Source Fudan University
Contact Zhimin Shao, MD
Phone +86-021-64175590
Email zhimingshao@yahoo.com
Status Recruiting
Phase Phase 2
Start date June 1, 2023
Completion date July 1, 2028

See also
  Status Clinical Trial Phase
Recruiting NCT05528263 - Preventing Chemotherapy-Induced Peripheral Neuropathy With Acupuncture (PACT Trial) N/A
Recruiting NCT06064812 - A Phase I Clinical Trial of FWD1802 in Patients With ER+/HER2- BC. Phase 1
Terminated NCT04088435 - Xoft® Intraoperative Radiotherapy (IORT) for Patients With Early-Stage Breast Cancer
Terminated NCT03723863 - Occupational Therapist-Led Work Intervention in Facilitating Work Maintenance or Re-entry to the Workforce in Patients With Stage I to III Breast Cancer Undergoing Chemotherapy N/A
Completed NCT00393341 - Quantitation of Endothelial Progenitor Cells as Markers of Tumor Angiogenesis in Breast Cancer N/A
Active, not recruiting NCT04180579 - Safety of Lower Scalp Cooling Temperature to Prevent Hair Loss From Chemotherapy in Breast Cancer Patients N/A
Recruiting NCT06275126 - Optimizing Surgical Decisions in Young Adults With Breast Cancer N/A
Not yet recruiting NCT05724758 - Patient Reported Outcomes After Oncoplastic Breast Conserving Surgery
Active, not recruiting NCT03766009 - Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making N/A
Recruiting NCT05406531 - The Effectiveness of Psychological Interventions in Psycho-neuroendocrine-immune Network in Breast Cancer Survivors N/A
Recruiting NCT05898789 - Virtual Rehabilitation for Cancer Survivors N/A
Recruiting NCT06006806 - Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy N/A
Active, not recruiting NCT03927027 - Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection Phase 3
Recruiting NCT05288777 - Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer Phase 2/Phase 3
Not yet recruiting NCT06336538 - Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors N/A
Not yet recruiting NCT05887154 - Non Surgical Treatment (Microwave Ablation) of Breast Cancer N/A
Recruiting NCT05219695 - Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI) N/A
Completed NCT02639208 - Novel Social Media Intervention For Older Br CA Patients N/A
Not yet recruiting NCT06268665 - Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy Phase 2
Completed NCT02335671 - Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving Therapy N/A