Breast Cancer Stage I Clinical Trial
Official title:
Adjuvant Pyrotinib and Capecitabine For HER2 Positive Micro Invasive Breast Cancer
For patients with HER2-positive early-stage breast cancer, NCCN guidelines recommend chemotherapy plus targeted therapy as the standard adjuvant treatment for patients with tumors larger than 1 cm or lymph node-positive. The APT study enrolled patients with stage I HER2-positive breast cancer and has confirmed the efficacy and safety of intravenous chemotherapy combined with targeted therapy, but only 2.2% of the patients enrolled in microinvasion are enrolled, and there is a lack of large sample size data to provide a treatment reference for these patients. In order to further explore the optimal strategy for adjuvant therapy in this type of patient, we designed a new clinical trial to evaluate the efficacy and safety of oral capecitabine plus pyrotinib as adjuvant therapy in previous retrospective studies.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05528263 -
Preventing Chemotherapy-Induced Peripheral Neuropathy With Acupuncture (PACT Trial)
|
N/A | |
Recruiting |
NCT06064812 -
A Phase I Clinical Trial of FWD1802 in Patients With ER+/HER2- BC.
|
Phase 1 | |
Terminated |
NCT04088435 -
Xoft® Intraoperative Radiotherapy (IORT) for Patients With Early-Stage Breast Cancer
|
||
Terminated |
NCT03723863 -
Occupational Therapist-Led Work Intervention in Facilitating Work Maintenance or Re-entry to the Workforce in Patients With Stage I to III Breast Cancer Undergoing Chemotherapy
|
N/A | |
Completed |
NCT00393341 -
Quantitation of Endothelial Progenitor Cells as Markers of Tumor Angiogenesis in Breast Cancer
|
N/A | |
Active, not recruiting |
NCT04180579 -
Safety of Lower Scalp Cooling Temperature to Prevent Hair Loss From Chemotherapy in Breast Cancer Patients
|
N/A | |
Recruiting |
NCT06275126 -
Optimizing Surgical Decisions in Young Adults With Breast Cancer
|
N/A | |
Not yet recruiting |
NCT05724758 -
Patient Reported Outcomes After Oncoplastic Breast Conserving Surgery
|
||
Active, not recruiting |
NCT03766009 -
Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making
|
N/A | |
Recruiting |
NCT05406531 -
The Effectiveness of Psychological Interventions in Psycho-neuroendocrine-immune Network in Breast Cancer Survivors
|
N/A | |
Recruiting |
NCT05898789 -
Virtual Rehabilitation for Cancer Survivors
|
N/A | |
Recruiting |
NCT06006806 -
Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy
|
N/A | |
Active, not recruiting |
NCT03927027 -
Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection
|
Phase 3 | |
Recruiting |
NCT05288777 -
Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer
|
Phase 2/Phase 3 | |
Not yet recruiting |
NCT06336538 -
Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors
|
N/A | |
Not yet recruiting |
NCT05887154 -
Non Surgical Treatment (Microwave Ablation) of Breast Cancer
|
N/A | |
Recruiting |
NCT05219695 -
Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)
|
N/A | |
Completed |
NCT02639208 -
Novel Social Media Intervention For Older Br CA Patients
|
N/A | |
Not yet recruiting |
NCT06268665 -
Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy
|
Phase 2 | |
Completed |
NCT02335671 -
Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving Therapy
|
N/A |