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Clinical Trial Summary

This study is a single-center,blinded, efficacious, phase III randomized clinical trial initiated by investigators. The primary objective is to investigate the use of Surface Guided Radiation Therapy (SGRT) in combination with Deep Inspiration Breath Hold (DIBH) technique for left breast cancer treatment, compared to traditional laser alignment with free breathing treatment. This approach offers superior positioning accuracy and improved heart protection without any increase in radiation or adverse reactions.


Clinical Trial Description

This is an investigator-initiated blinded, efficacious, phase III randomized clinical trial study. The study hypothesis is that the use of Surface Guided Radiation Therapy (SGRT) in combination with the Deep Inspiration Breath Hold (DIBH) technique for left breast cancer treatment can improve positioning accuracy and heart protection without any increase in radiation or adverse reactions. The primary endpoint of this study is the accuracy of the treatment location and incidence of patient coronary events/myocardial perfusion decline. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05804916
Study type Interventional
Source Peking Union Medical College Hospital
Contact Xiaorong HOU, PhD
Phone +86-13811963013
Email hxr_pumch@163.com
Status Recruiting
Phase Phase 2/Phase 3
Start date April 1, 2022
Completion date April 1, 2027

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