Study Assessing QBS72S For Treating Brain Metastases

Status Recruiting

Clinical Trial Summary

This study is to evaluate the efficacy and safety of QBS72S in participants with advanced, relapsed, metastatic breast cancer with CNS involvement.

Clinical Trial Description

Primary Objective 1. Test of the preliminary efficacy of the intracranial anti tumor activity of QBS72S through overall response rate (ORR) in Cohort 1 (Stages 1+2). Secondary Objectives 1. Test of the preliminary efficacy of the intracranial anti tumor activity of QBS72S through progression free survival (PFS) in Cohort 1 (Stages 1+2). 2. Test of the preliminary efficacy of the intracranial anti tumor activity of QBS72S through overall survival (OS) in Cohort 1 (Stages 1+2). 3. Test of the preliminary efficacy of the intracranial anti tumor activity of QBS72S through durations of response (DoR) in Cohort 1 (Stages 1+2). 4. Evaluate safety of QBS72S treatment in Cohort 1 (Stages 1+2), Cohort 2, and Cohort 3. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05305365
Study type	Interventional
Source	Stanford University
Contact	Kriti Lalwani
Phone	650-736-6489
Email	kritil@stanford.edu
Status	Recruiting
Phase	Phase 2
Start date	August 16, 2022
Completion date	August 2026

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