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CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer

Breast Cancer Clinical Trial

Official title:
A Dose-confirming Study of CFI-402257 as a Single Agent in Advanced Solid Tumors and in Combination With Fulvestrant in Patients With ER+/HER2- Advanced Breast Cancer After Disease Progression on Prior CDK4/6 and Endocrine Therapy

Clinical Trial Summary

The purpose of this study is to test the safety of an investigational drug called CFI-402257 alone in advanced solid tumors and in combination with Fulvestrant in advanced breast cancer patients.

Clinical Trial Description

This study will be evaluating the safety and tolerability of CFI-402257 in subjects with advanced solid tumors and in advanced breast cancer. The study is designed to build on encouraging data from another study and to obtain further safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) data of CFI-402257. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05251714
Study type Interventional
Source Treadwell Therapeutics, Inc
Contact Treadwell Therapeutics Clinical Trials
Phone +1-416-455-7510
Email clinicaltrials@treadwelltx.com
Status Recruiting
Phase Phase 1/Phase 2
Start date May 27, 2022
Completion date August 2025
View Details
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