Nab-paclitaxel Dose Schedual for HER-2 Negative Advanced Breast Cancer

Status Active, not recruiting

Clinical Trial Summary

What is the best dosage of Nab-Paclitaxel for chinese? This study would divide patients into two dosage groups: 1) 125mg/m2, 30 minutes intravenous injection, d1, 8, 21 days for a cycle(clinical use); 2) 125mg/m2 d1, 8, 15, 30 minutes intravenous injection, 28 days for a cycle(guideline recommand). Treatment to disease progression. The efficacy (CR, PR, SD, PD) is evaluated every 2-4 cycles.If the patient withdraws from the trial because he cannot tolerate the toxicity caused by one of the drugs, such as neurotoxicity or bone marrow toxicity, it is recommended to switch to other drugs and follow up to PFS and OS.Each group was planned to include 30 patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04192331
Study type	Interventional
Source	Peking University Cancer Hospital & Institute
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	February 21, 2019
Completion date	January 26, 2023

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