Breast Cancer Clinical Trial
Official title:
The Effects of Anesthetics on Persistent Pain Following Breast Cancer Surgery
Persistent postoperative pain occurs up to 25 to 60 % after mastectomy. This occurs at a
higher frequency than the rate of invasive surgery.Therefore, many ways have been tried to
study risk factors. A study was conducted to predict postoperative pain for items
(preoperative pain, sensitivity, pain prediction). As a result, it was reported that the
scope of surgery, pre-operative pain, young age, and depression were associated with
persistent pain.
This study try to find out whether persistent pain after mastectomy is affected anesthetic
factors appropriate anesthesia depth and opioid using standardized monitoring devices limited
to similar surgical ranges.
Persistent postoperative pain occurs up to 25 to 60 % after mastectomy. This occurs at a
higher frequency than the rate of invasive surgery.Therefore, many ways have been tried to
study risk factors. A study was conducted to predict postoperative pain for items
(preoperative pain, sensitivity, pain prediction). As a result, it was reported that the
scope of surgery, pre-operative pain, young age, and depression were associated with
persistent pain.
There were reports of no association with anesthesia in the area of anesthesia to the high
pain control requirement in the postoperative recovery room, 24 hours of high pain
medication, use of inhalation agent, and a high dosage of remifentanil. However, an
anesthesia-related study was either a retrospective study or anesthetic was injected with
more than a clinical dose in order to make the difference following methods.
In this study, bispectral index is used to maintain anesthesia depth. In addition, the
commercially available noninvasive pain depth equipment (Surgical Pleth Index) is used to
assess the nociception-antinociception balance. Displays the automatically calculated values
of SPI=100-(0.3*heartbeat interval + 0.7*photoplethysmographic pulse wave ampule) using a
waveform with peripheral oxygen saturation. Through this process, patients want to objectify
the amount of anesthetic agent used during surgery. And all patients are inserted the
laryngeal mask airway.
This study would try find out whether persistent pain after mastectomy is affected anesthetic
factors appropriate anesthesia depth and opioid using standardized monitoring devices limited
to similar surgical ranges.
The investigators hypothesize that patients who suffered severe acute postoperative pain,
regardless of their anesthesia method, have a higher incidence of persistent post-mastectomy
pain.
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