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Clinical Trial Summary

This study will compare DS-8201a to physician choice standard treatment. Participants must have HER2-low breast cancer that has been treated before. Participants' cancer: - Cannot be removed by an operation - Has spread to other parts of the body


Clinical Trial Description

This is a randomized, 2-arm, Phase 3, open-label, multicenter study to compare the safety and efficacy of trastuzumab deruxtecan versus the physician's choice (2:1) in HER2-low, unresectable and/or metastatic breast cancer participants. The Sponsor proposes to define a new HER2-low population in this trial including tumors with IHC 1+ and IHC 2+/ISH- HER2 expression. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03734029
Study type Interventional
Source Daiichi Sankyo
Contact
Status Active, not recruiting
Phase Phase 3
Start date December 27, 2018
Completion date October 1, 2025

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