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A Biomarker Study of Palbociclib + Fulvestrant for Second, and Third Line of Postmenopausal Women With hr+/her2- Advanced Breast Cancer — PALPETBIO  

Breast Cancer Clinical Trial

Official title:
A Biomarker Study of Palbociclib + Fulvestrant for Second, and Third Line of Postmenopausal Women With hr+/her2- Advanced Breast Cancer (PALPETBIO)

Clinical Trial Summary

The clinical efficacy of fulvestrant and/or palbociclib in the population of patients with metastatic lesions harboring ESR1 mutations was reported. In the PALOMA 3 study, the combination of Fulvestrant+ Palbociclib seems to be active in patients whose tumour harbours ESR1 mutations. This study will confirm these data on this population and will allow us to identify if other gene alterations or a genomic signature can correlate with fulvestrant +palbociclib resistance.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03560856
Study type Interventional
Source Assistance Publique - Hôpitaux de Paris
Contact TEIXEIRA LUIS, MD PhD
Phone 142499613
Email luis.teixeira@aphp.frluis.teixeira@aphp.fr
Status Not yet recruiting
Phase Phase 2
Start date June 27, 2018
Completion date June 1, 2022
View Details
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