Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block in Breast Cancer Patients

Breast Cancer Patients Clinical Trial

Official title: Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block in Patient Undergoing Breast Cancer Surgery :A Comparative Study

Status Recruiting

Clinical Trial Summary

To Evaluate the effect of addition of Dexmedetomedine to ultrasound guided modified Pecs block on post operative analgesia & stress response in patient undergoing modified radical mastectomy.

Clinical Trial Description

60 patients (age ≥29 years) who scheduled for modified radical mastectomy surgery under general anesthesia. Group I (Bupivacaine group): patients underwent modified radical mastectomy were given preoperative ultrasound guided modified Pecs block with 30 mL of 0.25% bupivacaine divided into 10 ml injected between the pectoralis muscles on the interfasial plane, and 20 ml injected between the Pectoralis minor muscle and the serratus muscle.Group II (Bupivacaine + Dexmedetomidine group) : preoperative ultrasound guided modified Pecs block with 30 mL of 0.25% bupivacaine plus Dexmedetomidine (1 µg/kg) divided into 20 ml injected between the pectoralis muscles on the interfasial plane , and 10 ml injected between the Pectoralis minor muscle and the serratus muscle. ;

Related Conditions & MeSH terms

• Breast Cancer Patients
• Breast Neoplasms

• NCT number: NCT03046238
• Study type: Interventional
• Source: South Egypt Cancer Institute
• Contact: mohamad F mohamad, MD
• Phone: +201093942354
• Email: mfaroukma@gmail.com
• Status: Recruiting
• Phase: Phase 3
• Start date: February 2, 2017
• Completion date: April 2, 2017