Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help in Treatment for Breast Cancer

Breast Cancer Clinical Trial

— MBSR  

Official title:

Effect of a Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help to Improve Exercise Capacity and Quality of Life in Breast Cancer

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02900326
• Other study ID #: 5970
• Status: Completed
• Phase: N/A
• Start date: May 12, 2015
• Est. completion date: March 30, 2021

Study information

• Verified date: May 2022
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Integrative approaches to promote wellness and reduce the distress associated with cancer are considered as essential components of cancer care. In case, exercise training has been shown to produce many positive physiological and psychological benefits. Mindfulness-based stress reduction program shows similar beneficial effects, and especially in emotional distress management. The aim of the study is to examine the cumulative effect of an 8 week-exercise-training program combined with an MBSR program on cardio-respiratory fitness and quality of life in women with breast cancer. These effects are thought to be mediated in part through changes in underlying brain processes, that investigators will be put in light. Through telomerase activity, oxidative stress, mitochondrial respiration and blood cytokine level measurements, investigators could expect to better understand the effect of these combined training in breast cancer.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: March 30, 2021
• Est. primary completion date: May 12, 2015
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Breast cancer

• Having completed the chemotherapy period

• Undergoing radiotherapy and/or hormono therapy

Exclusion Criteria:

• Regular physical activity higher than 4 hours per week.

• Any disease cardiac, respiratory, neurological or articular disease, which counteract the muscular training )

Related Conditions & MeSH terms

• Breast Cancer
• Breast Neoplasms

Intervention

Other:
• Endurance exercise training
In each group, there will be a comparison of aerobic capacity, quality of life (with questionnaires), functional cerebral measurements (fRMI), and telomerase activity between before and after the 8 weeks program
• Mindfulness-based-stress-reduction

• Both interventions together

• Vo2max measurements

Genetic:
• Telomerase activity on a blood sample

Other:
• Quality of life (questionnaires)

• Cerebral IRMf

Locations

Country	Name	City	State
France	Physiologie et EFR/ EA 3072 mitochondrie, stress oxydant et protection musculaire	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Evolution of V02 max between inclusion and 8 weeks	effect of physical training associated with mental work on physical abilities of patients	8 weeks