Vascular Changes Due to Different Treatments of Lymphedema Secondary to Postoperative Breast Cancer

Breast Cancer Clinical Trial

Official title: Vascular Changes Due to Different Treatments of Lymphedema Secondary to Postoperative Breast Cancer

Status Not yet recruiting

Clinical Trial Summary

The objective of this study is to evaluate the effect of elastic compression, functional compressive bandaging (ECF) and active exercises in the bloodstream of the upper member ipsilateral to the surgical procedure for the treatment of breast cancer.

Clinical Trial Description

With increasing survival of women treated for breast cancer, it becomes necessary to evaluate the effect of therapeutic resources in morbidity due to surgical treatment of breast cancer. The objective of this study is to evaluate the effect of elastic compression, functional compressive bandaging (ECF) and active exercises in the bloodstream of the upper member ipsilateral to the surgical procedure for the treatment of breast cancer. The study will be conducted according to design random cross over and wash out period of 7 days. They will be evaluated 30 volunteers aged between 45 and 70 years, submitted to treatment of breast cancer. The volunteers will be submitted to three different therapeutic procedures applied randomly by lot: active exercises, functional compressive bandaging with active exercises and elastic compression with active exercises. The profile of blood flow, including speed and direction, will be assessed by Doppler ultrasound before and after, at 0, 15, 30 minutes. Normality will be verified by the Shapiro-Wilk test, and the effect of behavior between pre- and post-intervention will be evaluated by ANOVA two-way followed by post-hoc test Friedman followed rank, p <0.05 . The data obtained in the study are intended to enhance the forms of physical therapy intervention in the face of circulatory morbidities resulting from breast cancer treatments. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator)

Related Conditions & MeSH terms

• Breast Cancer
• Breast Neoplasms
• Lymphedema

• NCT number: NCT02517086
• Study type: Interventional
• Source: University of Sao Paulo
• Contact: Elaine Guirro
• Phone: (16)33150215
• Email: ecguirro@fmrp.usp.br
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 2015
• Completion date: July 2016