Breast Cancer Clinical Trial
Official title:
Pilot Study to Investigate the Impact of Hypochlorite in the Prevention of Radiation Dermatitis
This pilot clinical trial studies Dakin's solution in preventing radiation dermatitis in patients with breast cancer undergoing radiation therapy. Radiation dermatitis is a skin condition in which the affected skin becomes painful, red, itchy, and blistered. Dakin's solution may help reduce dermatitis caused by radiation therapy.
PRIMARY OBJECTIVES:
I. To determine the percent change in women who experience grade 3 or 4 radiation dermatitis
as defined by the Stanford Radiation Dermatitis Scoring System during radiation treatment
for breast cancer compared to historical experience using standard skin care.
SECONDARY OBJECTIVES:
I. To assess the feasibility of daily application of the hypochlorite solution (Dakin's
solution), and to assess levels of pain during radiotherapy treatment.
OUTLINE:
Patients apply Dakin's solution topically daily over 10 minutes within 60 minutes of
radiation therapy for up to 6 weeks.
After completion of study treatment, patients are followed up at 4-6 weeks.
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
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