Breast Cancer Clinical Trial
Official title:
The Effectiveness of 18F-FDG PET Metabolic Phenotype in Evaluating Therapeutic Response for Breast Cancer Patients With Bone Metastases.
This study is to evaluate the effectiveness of 18F-FDG PET in following up of metastastic
bone lesions and in predicting outcome for breast cancer patients after therapy.
Primary outcome: Using 18F-FDG uptake to evaluate the metastatic bone status after
treatment. The PET results will be compared with the results in Tc-99m MDP bone
scintigraphy.
Secondary outcome: Evaluate the relationship between the 18F-FDG uptake of the metastatic
bone lesions and (1) breast cancer related tumor marker, (2) patients' survival.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | August 2014 |
Est. primary completion date | August 2014 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 90 Years |
Eligibility |
Inclusion Criteria: 1. Age:20-90 years old 2. Histological proven breast cancer, with known metastatic bone lesion(s) 3. written informed consent signed Exclusion Criteria: 1. pregnant or intend to be pregnant 2. other malignancies known |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Taiwan | National Taiwan University Hospital | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital |
Taiwan,
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Du Y, Cullum I, Illidge TM, Ell PJ. Fusion of metabolic function and morphology: sequential [18F]fluorodeoxyglucose positron-emission tomography/computed tomography studies yield new insights into the natural history of bone metastases in breast cancer. J Clin Oncol. 2007 Aug 10;25(23):3440-7. Epub 2007 Jun 25. — View Citation
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* Note: There are 13 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The uptake of 18F-FDG PET. | 2 hours | No |
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