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Oral Vinorelbine in Combination With Trastuzumab for Metastatic Breast Cancer — OVINTRA  

Breast Cancer Clinical Trial

Official title:
A Phase II Investigation of Oral Vinorelbine in Combination With Trastuzumab for 1st and 2nd Line Treatment of Women With Metastatic HER2 Positive Breast Cancer

Clinical Trial Summary

This phase II study will investigate oral vinorelbine 90 mg/m2 on days 1 + 8 at 3 weeks intervals in combination with trastuzumab as 1st and 2nd line treatment of women with metastatic HER2 positive breast cancer.

Oral vinorelbine has shown the same overall response rate as i.v. vinorelbine in metastatic breast cancer, and capsules are generally better tolerated.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01242449
Study type Interventional
Source Vejle Hospital
Contact
Status Completed
Phase Phase 2
Start date November 2010
Completion date October 2014
View Details
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