Breast Cancer Clinical Trial
Official title:
A Correlative Science Study for ECOG E5194
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may
help doctors learn more about changes that occur in DNA and identify biomarkers related to
cancer.
PURPOSE: This research study is studying biomarkers in tissue samples from patients with
ductal breast carcinoma in situ.
OBJECTIVES:
- To validate the prognostic utility of a new ductal breast carcinoma in situ (DCIS)
genomic score and the Oncotype DX Recurrence Score® assay in tissue samples from
patients with DCIS enrolled on clinical trial ECOG-E5194.
OUTLINE: RNA extracted from archived tissue samples are analyzed for gene expression profile
by Oncotype DX Recurrence Score® assay (a reverse transcriptase-PCR-based assay).
;
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