Male Breast Cancer: Understanding the Biology for Improved Patient Care

Status Active, not recruiting

Clinical Trial Summary

Rationale: Gathering medical information and tumor samples from patients with male breast cancer may help doctors learn more about the disease. Purpose retrospective part: to perform a large international retrospective analysis of clinical and biological data of male BC patients treated in the participating centers from 1990 to 2010. Purpose prospective part: to create a registry of men with breast cancer for a period of 30 months (starting early 2014).

Clinical Trial Description

Objectives retrospective part (closed to patients registration in September 2013): - To perform a large international joint retrospective analysis of clinical and biological data of male breast cancer (BC) patients treated from 1990 to 2010. - To create a database of patient characteristics, disease features, treatments received, and clinical outcomes of a large series of men diagnosed with BC from 1990 to 2010 in centers in Europe and USA. - To perform a central pathological review of the corresponding large series of male BC tumors to determine their biologic characteristics and identify relevant prognostic and predictive markers. Objectives prospective part (opened early 2014): - To run a prospective registry of all male BC patients (including newly diagnosed) irrespective of the stage and treatment, in the participating institutions for a period of 30 months; collection of FFPE, fresh frozen and blood samples is optional but highly encouraged. - Quality of Life sub-study The two parts of this study will provide important information regarding male BC biology and clinical evolution. The collected follow-up information will provide an overview of the current practice in the early and the advanced disease and also offer precious information of the disease evolution in such rare patients' population. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01101425
Study type	Observational [Patient Registry]
Source	European Organisation for Research and Treatment of Cancer - EORTC
Contact
Status	Active, not recruiting
Phase
Start date	December 2010
Completion date	March 2024

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