Breast Cancer Clinical Trial
Official title:
Effect of Acupuncture on Brain Serotonin Among Breast Cancer Survivors
RATIONALE: New imaging procedures, such as single photon emission computed tomography, may help in learning how acupuncture affects serotonin levels in the brain of breast cancer survivors. PURPOSE: This phase I trial is studying the best way to visualize the effect of acupuncture on brain serotonin in breast cancer survivors.
Detailed Description
OBJECTIVES:
I. To determine the feasibility of using [123-I] ADAM Serotonin transporter (SERT) binding
as a putative biomarker to visualize the mechanism of effects of acupuncture for hot flashes
involving serotonin.
OUTLINE: Patients undergo acupuncture twice weekly for 2 weeks and then once weekly for 6
weeks. Patients undergo single photon emission computed tomography imaging with iodine 123-I
ADAM before and after completion of acupuncture.
After completion of study treatment, patients are followed for 4 weeks.
;
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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