Breast Cancer Clinical Trial
Official title:
Efficacy of Topical Bimatoprost in Promoting Hair Growth in the Region of the Eyebrow and Eyelashes for Post-chemotherapy Patients Versus Normal Patients
RATIONALE: Bimatoprost ophthalmic solution may help increase eyebrow and eyelash growth in
patients who have undergone chemotherapy.
PURPOSE: This randomized clinical trial is studying how wells bimatoprost ophthalmic solution
works in increasing eyebrow and eyelash growth in patients who have undergone chemotherapy
for breast cancer and in healthy participants.
OBJECTIVES:
Primary
- To assess the effectiveness of bimatoprost ophthalmic solution in expediting regrowth of
eyebrows and eyelashes in patients who have undergone chemotherapy for breast cancer and
in increasing eyebrow growth in healthy participants with no known underlying disease as
assessed by two physicians and an aesthetics expert on a scale of 0-4.
Secondary
- To assess the effectiveness of this treatment as assessed by patient self-report on a
scale of 0-4.
- To assess the psychological impact of this treatment as assessed by patient-completed
questionnaires.
OUTLINE: Patients are randomized to 1 of 2 intervention arms.
- Arm I: Patients apply topical bimatoprost ophthalmic solution to base of upper eyelid
margins OR to eyebrow region once daily for 4 months in the absence of unacceptable
toxicity.
- Arm II: Patients apply topical placebo solution to base of upper eyelid margins OR to
eyebrow region once daily for 4 months in the absence of unacceptable toxicity.
Patients complete questionnaires at baseline and monthly for 5 months about changes in
eyebrows/eyelashes, side effects of treatment, and the psychological impact of treatment.
Photographs of eyebrows or eyelashes and surrounding skin are taken at baseline and monthly
for 5 months and reviewed by a physician and aesthetics expert.
After completion of study treatment, patients are followed up at 1 month.
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