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Clinical Trial Summary

RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about nutrition-related changes that identify biomarkers related to cancer. It may also help doctors predict a woman's risk of developing breast cancer.

PURPOSE: This laboratory study is looking at nutrition-related biomarkers in predicting breast cancer risk in women.


Clinical Trial Description

OBJECTIVES:

- To complete characterization of metabolic serotypes based on the metabolome, and to adapt these profiles for human epidemiological studies.

- To determine the extent to which metabolic profiles that are reflective of or independent of long-term caloric intake predict breast cancer risk in nested case-control studies.

- To identify critical serum metabolites.

OUTLINE: Laboratory studies, including metabolome profiling by high performance liquid chromatography; and small molecule identification by mass spectroscopy, are performed on previously collected blood samples. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00900367
Study type Observational
Source Brigham and Women's Hospital
Contact
Status Active, not recruiting
Phase
Start date July 2005
Completion date December 31, 2025

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