Breast Cancer Clinical Trial
Official title:
A Pilot Trial to Correlate Serum Levels of Calgranulin A and B With Estrogen Receptor Status Among Patients With Breast Cancer
RATIONALE: Measuring levels of calgranulin A and calgranulin B in the blood of patients with
breast cancer in the laboratory may help doctors identify and learn more about biomarkers
related to breast cancer.
PURPOSE: This laboratory study is measuring calgranulin A and calgranulin B levels in the
blood of patients with newly diagnosed stage I, stage II, or stage III breast cancer.
OBJECTIVES:
- Determine circulating levels of calgranulin A and calgranulin B in patients with
estrogen receptor negative or estrogen receptor positive, newly diagnosed, primary
stage I-III adenocarcinoma of the breast.
OUTLINE: This is a pilot study.
Patients undergo a blood draw following diagnosis of breast cancer to assess levels of
circulating tumor markers, calgranulin A and calgranulin B. Serum samples are evaluated by
enzyme-linked immunosorbent assay for tumor marker expression.
PROJECTED ACCRUAL: A total of 60 patients will be accrued for this study.
;
Observational Model: Case-Only, Time Perspective: Cross-Sectional
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