Effect of Combined Aerobic and Resisted Exercise in Breast Cancer Survivors

Breast Cancer Clinical Trial

Official title:

Effect of Combined Aerobic and Resisted Exercise in Breast Cancer Survivors: Upper Extremity Function, Quality of Life and Fitness Outcomes

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00877188
• Other study ID #: 200808034R
• Secondary ID: NTUH98-M1178
• Status: Completed
• Phase: N/A
• First received: March 22, 2009
• Last updated: December 20, 2012
• Start date: January 2009
• Est. completion date: December 2010

Study information

• Verified date: November 2012
• Source: National Taiwan University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the effects of a combined aerobic and resistance exercise program in breast cancer survivors.

Description:

Cancer and cancer treatment side effects are associated with fatigue, pain, decreased cardiovascular fitness and muscle strength, and overall quality of life. Furthermore, cancer survivors are at increased risk for cancer recurrence and for secondary effect such as cardiovascular disease, diabetes, obesity, osteoporosis, and functional decline. Increase physical activity or exercise is proposed to overcome the negative psychological and physiological effects. Preliminary research evidence shows that exercise in cancer survivors improves quality of life, cardiorespiratory fitness, physical functioning, and decrease of fatigue. However, the best exercise mode and intensity has not been well established. Little is known regarding the long term effect. No study investigated impact of exercise for breast cancer survivors on upper extremity function, and correlation between fitness, upper extremity function and quality of life.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: December 2010
• Est. primary completion date: October 2010
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• stage 0 to II breast cancer diagnosed within 5 years

• complete adjuvant therapy > 2 months, except hormone therapy

• > 18 years

Exclusion Criteria:

• disease in progress, recurrent, or metastasis

• medical or musculoskeletal condition which resistance exercise is contraindicated

• medication which may alter exercise response

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Breast Cancer
• Breast Neoplasms
• Exercise
• Physical Function

Intervention

Other:
• exercise
supervised combined aerobic and progressive resistance training for 12 weeks

Locations

Country	Name	City	State
Taiwan	Graduate School of Physical Therapy, College of Medicine, NTU	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	muscle fitness, quality of life, upper extremity function		baseline, 12 weeks post exercise training and follow up 12 weeks	Yes