Breast Cancer Clinical Trial
Official title:
Partial Breast Irradiation for Patients Undergoing Breast Conservation Therapy for Early Stage Breast Cancer: A Pilot Study
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill
tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
PURPOSE: This clinical trial is studying how well partial breast radiation therapy works in
treating women undergoing breast-conserving therapy for early stage breast cancer.
OBJECTIVES:
- To determine the cosmetic outcome resulting from partial breast irradiation using two
different techniques.
- To determine patient satisfaction with partial breast irradiation as it pertains to
their overall treatment experience as measured by a questionnaire.
- To determine if there are patient factors that limit a patient's suitability to receive
partial breast irradiation delivered by a particular technique.
- To evaluate wound healing and overall complication rate after partial breast
irradiation.
- To determine ipsilateral breast tumor recurrence rates and tumor bed recurrence rates.
OUTLINE: Patients undergo partial breast irradiation comprising either MammoSite®
brachytherapy twice daily for 5-10 days OR 3-dimensional conformal radiotherapy twice daily
for 5-10 days.
After completion of study therapy, patients are followed periodically for up to 5 years.
;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
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