Breast Cancer Clinical Trial
Official title:
Case-Control-Study on the Breast Cancer Risk of Mirena® Compared With Copper IUDs
The objective of this study is to determine the breast cancer risk of Mirena® users compared to copper intrauterine device (IUD) users in a community-based case-control study.
This is a community-based case-control study in Germany and Finland. Cases will be
identified from cancer registries, tumor centers and breast centers. Matched controls will
be accrued from the same region as the case came from. Breast cancer cases and their
controls are women under 50 years of age without known history of malignancies.
Cases are women with a breast cancer who are younger than 50 years of age at cancer
diagnosis. The breast cancer was diagnosed between January 2000 and December 2007. Only
alive cases and cases in a sufficiently good health status to be interviewed are eligible
for the study.
Controls are women without a breast cancer diagnosis who are younger than 50 years of age at
the time of the interview. About 3 controls matched by year of birth and region will be
allocated to each case.
A standardized questionnaire will be used for all breast cancer cases and controls. The
questionnaire will be mailed to cases and controls.
Study participants will be asked for their informed consent. Data confidentiality according
to national laws will be ensured by the field organizations.
;
Observational Model: Case Control
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