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Phase II Study of T-DX in HER2-positive Breast Cancer Brain Metastases — TUXEDO-1  

Breast Cancer Stage IV Clinical Trial

Official title:
Phase II Study of Trastuzumab-Deruxtecan (T-DX; DS-8201a) in HER2-positive Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases

Clinical Trial Summary

Trastuzumab-Deruxtecan (T-DXd; DS-8201a) in HER2-positive Breast Cancer Patients with newly diagnosed or progressing Brain Metastases

Clinical Trial Description

T-DXd will be administered at a dose of 5.4 mg/kg body weight once every three weeks in patients with newly diagnosed or progressive HER2 positive breast cancer brain metastases. Response rate by RANO-BM is defined the primary study endpoint. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04752059
Study type Interventional
Source Medical University of Vienna
Contact
Status Completed
Phase Phase 2
Start date July 28, 2020
Completion date May 1, 2023
View Details
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