Breast Cancer Lymphedemas Clinical Trial
Official title:
Relationship Between Bioelectrical Impedance Utilization and Dietary Intake in the Analysis of Risk of Lymphedema in Breast Cancer Survivors: A Prospective Cross Sectional Study
The purpose of this study was to investigate the clinical role of bioelectrical impedance analysis (BIA) and the relationship between the occurrence of breast cancer related lymphedema (BCRL) and dietary factors in breast cancer survivors who underwent surgical treatments.
Breast cancer survivors are at risk of complications of breast cancer-related lymphedema
(BCRL) after surgical treatments, which may negatively effect on the quality of life of
breast cancer survivors. Lymphedema has been clinically diagnosed by determining that a limb
is in fact swollen, and has arbitrarily been diagnosed in other etiologies. Limb
circumference differences of 2 cm, a 200 mL or more in limb, or a 5% volume change are some
of the objective ways that clinicians use to diagnose lymphedema. Although the arm
circumference measurement method is a simple and frequently used clinical method, there is a
disadvantage that the standardized reference point does not exist, the extracellular space
can not be measured, and the sensitivity is also low. The lack of evidence-based diagnostic
criteria to define lymphedema has presented tremendous difficulty in diagnosing lymphedema.
It is important to define such criteria for early detection and treatment of lymphedema.
Because of these limitations, many researchers are studying various methods for diagnosing
lymphadenopathy and methods of bioelectrical impedance have been studied, recently.
Bioelectrical Impedance predicts body composition using the difference of electric
conductivity by flowing a minute current to human body.This principle is used to diagnose the
occurrence of lymphatic edema. In several studies, the single-frequency bioimpedance analysis
(SFBIA) of the two arms obtained from bioelectrical impedance measurements was expressed as
the ratio of the values of the operated and non-operated arms. However, it has not yet been
clarified as a diagnostic method. Therefore, more studies are needed to establish a diagnosis
method and a prediction method of lymphatic edema.
Various risk factors of lymphedema such as axillary lymph node dissection (ALND) and obesity
have been studied for early prevention. However, there are no studies on the relationship
between breast cancer related lymphedema, and dietary factors in breast cancer patients. The
purpose of this study was to compare the diagnosis of lymphedema with the measurement of the
arm circumference and the diagnosis of lymphedema through bioelectrical impedance values in
order to clarify the clinical role of bioelectrical impedance method as a diagnostic method
of lymphedema. To investigate the relationship between dietary factors, which are considered
to be related to the occurrence of lymphedema, the investigators examined the frequency of
dietary intake and analyzed the relationship between dietary factors and lymphatic edema.
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