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IGF Level in Breast Cancer Patients Treated With Metformin

Breast Cancer Female Clinical Trial

Official title:
Metformin Effect as a Chemotherapeutic Adjuvant on Level of IGF in Non-diabetic Breast Cancer Patients

Clinical Trial Summary

The purpose of this study is to examine the impact of metformin as an adjuvant to chemotherapy on IGF levels in both progressing and non progressing cases of metastatic breast cancer in female patients.

Clinical Trial Description

One hundred and seven women with metastatic breast cancer (MBC) are randomly assigned to either a metformin (500 mg twice daily) or placebo (placebo) group during chemotherapy. All patients followed the standard chemotherapy protocol developed by the South Egypt Cancer Institute (SECI). Blood IGF-1 levels were measured at the start of treatment (baseline) and again six months later. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05840068
Study type Interventional
Source Beni-Suef University
Contact
Status Completed
Phase Phase 4
Start date June 1, 2020
Completion date July 31, 2021
View Details
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