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Brain Tumour clinical trials

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NCT ID: NCT05981170 Not yet recruiting - Metastatic Cancer Clinical Trials

Rurality Adapted Physical Activity Sport Health

RAPASS
Start date: September 2023
Phase:
Study type: Observational

Physical activity (PA) has been an integral part of non-drug therapy since the early 2010s. This supportive care is likely to reduce fatigue and improve the quality of life of patients during and after the cancer treatment phase. Physical activity also has a protective effect in terms of tertiary prevention by reducing the risk of recurrence of certain cancers (breast, colon, prostate) by around 40 to 50% and by reducing overall mortality. Adapted physical activity (APA) is offered at the Institut de Cancérologie de l'Ouest (ICO) in Angers, but there are obstacles particularly linked to the geographical distance of the establishment where this activity is offered. The RAPASS project is a prospective study which will be proposed to patients followed at the ICO, living in rural areas and far from Angers. Its main objective is to describe the fatigue and quality of life of patients before, during and after a 13-session home-based APA programme. The data collected will also be used to describe changes in physical condition and level, compliance with the programme, continuation of physical activity beyond the duration of the programme, and satisfaction.

NCT ID: NCT04734444 Recruiting - Glioblastoma Clinical Trials

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The objective of this clinical investigation is to assess the safety and performance of the SonoClear Acoustic Coupling Fluid (ACF). The performance will be assessed by analysis of the contrast-to-noise ratio (CNR) and assessment of image quality by using the Surgeon Image Rating (SIR) Scale. This is a prospective, multi-centre single-arm study where the performance of SonoClear ACF relative to routinely used acoustic coupling fluid is investigated by each patient being their own control. Patients with the diagnosis of HGG and LGG at up to 10 sites will be included. Additionally, safety data are collected at 30 days and 6 months post-procedure.

NCT ID: NCT04712214 Recruiting - Glioma Clinical Trials

Use of Non-invasive Optical Analysis in Neurosurgery

Start date: March 28, 2021
Phase: N/A
Study type: Interventional

The present study aims to investigate the potential application of multispectral analysis, hyperspectral imaging, and fluorescence during neuro-oncological procedures, specifically during brain tumour debulking / resection. These optics techniques are entirely non-invasive and consist in camera with a filter to be linked to the standard microsurgical and endoscopic instruments used in theatre. The research procedure consists of images acquisition and data processing, with virtually no additional invasive procedures to be performed on patients.

NCT ID: NCT02792608 Completed - Depressive Symptoms Clinical Trials

Mindfulness-Based Therapy for Brain Tumour Survivors

Start date: August 2016
Phase: N/A
Study type: Interventional

Brain Tumour (BT) survivors struggle with disabling physical, emotional, cognitive and psychosocial sequelae. Unfortunately, to-date there has been very limited research into rehabilitative interventions for this population. With 55,000 BT survivors in Canada alone1, access to effective, evidence-based rehabilitative treatment that would improve BT survivors' quality of life (QOL) and capacity to cope is a necessity. Mindfulness-Based Therapy's (MBTs) are emerging as a potential treatment to address this need. MBTs are group-based psychological treatments for coping with illness or disability, with the goal of improving psychological wellbeing. Recent studies have begun to suggest a role for MBTs in addressing symptom burden and QOL in the acquired brain injury (ABI) population, a heterogeneous population that includes survivors of stroke and traumatic brain injury, as well as BT survivors. High quality research including within-subject controlled trials, are needed to demonstrate whether MBTs can provide efficacious, accessible and cost-effective treatment to improve the lives of BT survivors.

NCT ID: NCT02057367 Completed - Brain Tumour Clinical Trials

Scalp Nerve Block and Opioid Consumption in Brain Surgery

Start date: March 2013
Phase: Phase 4
Study type: Interventional

Anterior scalp block with 0.5% plain Marcaine 20 ml. may reduce the intraoperative opioid consumption in neurosurgical patients who undergoing the supratentorial craniotomy compared to those who receive 0.9% normal saline solution (placebo).

NCT ID: NCT00996450 Completed - Brain Tumour Clinical Trials

Educational Follow-up in a Cohort of Children at the Royal Marsden Hospital (RMH)

Start date: June 2008
Phase: N/A
Study type: Observational

To document pre-diagnosis educational abilities, to document any change in educational achievements following treatment, to document educational support given within the statement process and to document the timing of support.