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Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer

Brain Metastases Clinical Trial

Official title:
Whole Brain Irradiation With Hippocampal Sparing for Brain Metastases From Breast Cancer: Neurocognitive Function and Prognosis Analysis

Clinical Trial Summary

Based on evidence that radiation-induced damage to the hippocampus plays a considerable role in neurocognitive decline after cranial irradiation, hippocampal-sparing whole brain radiation therapy (HS-WBRT) has been proposed. This study will investigate the neurocognitive function and prognosis between HS-WBRT and conventional WBRT for the treatment of brain metastases from breast cancer.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03002532
Study type Interventional
Source Affiliated Hospital to Academy of Military Medical Sciences
Contact Zheng Jiang
Phone 861066947017
Email keyan307@163.com
Status Recruiting
Phase N/A
Start date August 2015
Completion date August 2017
View Details
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