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Brain Injuries, Traumatic clinical trials

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NCT ID: NCT05460728 Completed - Clinical trials for Traumatic Brain Injury

Dry Needling Effects Post-traumatic Brain Injury

Start date: April 5, 2022
Phase: N/A
Study type: Interventional

Thirty-six years old male with a history of TBI with compromised functionality of the right upper and lower limbs, spasticity, distributed balance, and difficulties performing independent gait has participated in the study. Berg balance scale, 6-minute walk test, modified Ashworth scale, and functional independence measure was used to assess balance, gait, spasticity, and functional intemperance, respectively.

NCT ID: NCT05457023 Completed - Brain Trauma Clinical Trials

Plasma Neurofilament Light and Its Relationship With Omega-3 Status and Soccer Heading in Women Soccer Players

Start date: July 28, 2022
Phase:
Study type: Observational

The purpose of this study is to (1) assess how a competitive season of purposeful gameplay soccer heading in collegiate women soccer players is related to a blood biomarker for sports-related brain injury, plasma neurofilament light (NF-L), and (2) examine how a player's omega-3 status is related to plasma NF-L concentration changes during and after a competitive season of gameplay soccer heading.

NCT ID: NCT05407948 Completed - Stroke Clinical Trials

The Effect of Cognitive Reserve on Outcome After Stroke or Traumatic Brain Injury

Start date: November 2, 2018
Phase:
Study type: Observational

A long-term follow-up study of patients who acquired a stroke or traumatic brain injury (TBI) 5-15 years ago. Primary objective is to describe the interaction between measures of cognitive reserve and neuropsychological variables, psychological variables and healthcare usage in relation to outcome (i.e work return, satisfaction with life, psychological well-being and overall outcome) after stroke or traumatic brain injury. Secondary objectives are to describe differences in fatigue related to cognitive reserve after stroke or TBI and to describe differences in health-care usage related to cognitive reserve after stroke or TBI.

NCT ID: NCT05405517 Completed - Clinical trials for Traumatic Brain Injury

Translation of Modified Fatigue Impact Scale in Urdu Language

Start date: May 15, 2021
Phase:
Study type: Observational

Cross cultural analytical study to translate Modified fatigue impact scale MFIS) in Urdu language. Along with the translated version by evaluating its validity and reliability among the patients of traumatic brain injury. No such study has been previously conducted in Pakistan which translate this scale in Urdu and follows the proper cross- culture adaptation.Condition or disease: Traumatic brain injury. Convenient sampling technique would be used.

NCT ID: NCT05397704 Completed - Clinical trials for Brain Injuries, Traumatic

Brain Oximeter Calibration and Validation Study

TPOT
Start date: October 10, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to calibrate and to validate the accuracy of the oximeter with an estimate of brain oxygen levels assessed by measuring arterial and internal jugular vein blood oxygen saturations.

NCT ID: NCT05391594 Completed - Cerebral Palsy Clinical Trials

Effect of Trunk Support on Academic Engagement of Children With Severe Disability

Start date: May 31, 2018
Phase: N/A
Study type: Interventional

This study evaluates the effect of optimizing trunk support based on segmental principles of trunk control, on academic engagement of children in academic settings.

NCT ID: NCT05315453 Completed - Clinical trials for Cognitive Impairment

Brief Telehealth Cognitive Rehabilitation Following Mild TBI

On-TRACC
Start date: December 13, 2021
Phase: N/A
Study type: Interventional

In the United States, more than a million people sustain a mild traumatic brain injury (mTBI) every year. Although many recover fully, emerging literature suggests a high number of individuals report chronic, and functionally disabling, cognitive difficulties. Among Veterans, a nationwide survey found that more than 75% of 55,000 Veterans with a history of mTBI reported persistent moderate to severe levels of forgetfulness and poor concentration. Reduced cognitive functioning following mTBI contributes to significant functional impairment, including underemployment, relationship difficulties, and reduced community integration for years post injury. Despite the significant individual and societal impact, evidence to guide interventions and treatment for this population remains limited. Even more limited are validated telehealth options for these symptoms, a critical means by which access to care can be improved, especially during the COVID-19 pandemic. The proposed pilot study will address this gap by evaluating the feasibility, acceptability, and preliminary effectiveness of a brief (5-session) cognitive rehabilitation intervention that was developed for individuals with mTBI and that will be administered over video-based telehealth technology. The development of this intervention was supported by a grant from the Department of Defense, with critical elements identified through surveys completed by clinicians and veterans with a history of mTBI, and also the clinical expertise of the team.

NCT ID: NCT05302362 Completed - Clinical trials for Traumatic Brain Injury

Effect of Fixed vs. Tailored Intensity tDCS for Attention Deficit After TBI

Start date: March 14, 2022
Phase: N/A
Study type: Interventional

Traumatic brain injury (TBI) is an important global health concern. Recently, advances in neurocritical care have led to an increase in the number of recovering TBI patients, and concomittantly in the incidence of complications of TBI. One of the most important sequalae of TBI is cognitive deficit, for which multimodal rehabilitation approach is indicated. Transcranial direct current stimulation (tDCS) is a promising treatment strategy for post-TBI cognitive deficits. However, a standardized tailored tDCS protocol is yet to be established for TBI patients. Therefore, this trial aims to 1) the efficacy of tDCS on post-TBI cognitive deficits, and 2) and optimized protocol of tDCS on post-TBI cognitive deficits via a three-arm double-blind, randomized controlled trial.

NCT ID: NCT05285774 Completed - Compliance, Patient Clinical Trials

Interest of the S100B Protein Assay in Mild Traumatic Brain Injuries at the DOUAI Hospital

PS100BTCL
Start date: April 6, 2022
Phase:
Study type: Observational

The main objective is to evaluate the feasibility and interest of setting up a protocol for the systematic measurement of the S100B protein in patients with mild traumatic brain injury admitted to the emergency room of Douai hospital in order to reduce the number of unnecessary brain scans. The main evaluation criterion is the percentage of patients admitted to the emergency department of Douai hospital for mild traumatic brain injury, whose protocol for the systematic measurement of the S100B protein would make it possible to avoid the realization of a brain scans for patients with a protein assay S100B ≤ 0.10 µg/L, carried out within 3h of the onset of MCT. The systematic dosage of the S100B protein in the context of mild traumatic brain injury still does not appear in the recommendations for good practice in 2021. This study will contribute to the reflection on the use of the S100B protein in the development of new recommendations for good practice of mild traumatic brain injury support.

NCT ID: NCT05217030 Completed - Clinical trials for Traumatic Brain Injury

Efficacy of Animal Assisted Therapy in the Treatment of Patients With Traumatic Brain Injury

AAT/TBI
Start date: June 30, 2014
Phase: N/A
Study type: Interventional

Patients admitted to the ED with moderate to severe traumatic brain injury defined by GCS less than or equal to 10 and confirmed by head CT scan or MRI were randomized into 2 groups: one receiving animal assisted therapy (AAT) and one not receiving animal assisted therapy. Efficacy of AAT was measured by patient's progression in the Glasgow Coma Scale (GCS), Rancho Los Amigos Scale (RLAS), and ability to follow multi-step commands (LoCmds).