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Bone clinical trials

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NCT ID: NCT06041087 Recruiting - Healthy Clinical Trials

Bone and Inflammatory Outcomes - Nutrition and Exercise Trials

BIONEX
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

This study investigates whether dairy products will positively impact loading exercise-induced bone turnover and bone cell activity and/or the post-exercise inflammatory response in healthy young adults compared to a carbohydrate drink and/or water.

NCT ID: NCT05805553 Recruiting - Growth Clinical Trials

Anabolic Steroid and Propranolol in Paediatric Burn

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

propranolol and anabolic steroids have a role in pediatric burn patients and their combined effects are to be studied here. They decrease the catabolic response to burn trauma and minimize the duration of growth arrest hence improving the outcome

NCT ID: NCT05034848 Terminated - Clinical trials for Peripheral Artery Disease

Peripheral Artery Disease (PAD) : Its Effects on Bone

AMICOS
Start date: March 31, 2021
Phase: N/A
Study type: Interventional

Prevalence of PAD and osteoporosis (OP) both get higher with age. Clinical and epidemiologic evidence have showed an increased cardiovascular risk in OP and bone loss and fragility fractures in patient with cardiovascular disease. This study will examine the relationship between vascular disease in legs and sBMD and vBMD at trabecular and cortical sites and bone microarchitecture.

NCT ID: NCT04018287 Active, not recruiting - Hypophosphatasia Clinical Trials

Circulating miRNAs and Bone Microstructure in Adults With Hypophosphatasia

Start date: August 1, 2017
Phase:
Study type: Observational

The aim of the study is to accomplish a complete bone status of patients with HPP using new approaches to assess bone quality.

NCT ID: NCT03615989 Terminated - Healthy Clinical Trials

The Combined Effect of Dairy and Exercise on Bone and Inflammation

Cre-Ex-Inf
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

This study analyzes whether dairy supplementation positively impacts loading exercise-induced bone cell activity and inflammation in healthy young females.

NCT ID: NCT03367169 Recruiting - Fractures Clinical Trials

Surgery of the Pilon Fractures

MICOPIL
Start date: November 23, 2017
Phase: N/A
Study type: Interventional

The assessment consists in comparing the osteosynthesis plate with minimally invasive technique versus open reduction and internal fixation. The aim of study is to compare (period of bandage, efficacy, safety), these two types of surgical technique by using a prospective, randomized analysis.

NCT ID: NCT02904421 Completed - Scoliosis Clinical Trials

6 Years Study on Changes in Bone Quality, Bone Turnover and Curve Severity in AIS With and Without Calcium and Vit-D Supplementation

Start date: October 2016
Phase:
Study type: Observational

The study aimed to: 1. To investigate and compare the changes in bone mineral density (BMD), trabecular bone micro-architecture, bone strength, and curve severity at a mean of 6 years longitudinal follow up in AIS girls with low bone mass between Group A and B: 1. Group A: subjects followed at a mean of 4 years after completion of 2-year calcium and Vit-D supplementation and 2. Group B: subjects without calcium and Vit-D supplementation 2. To evaluate the correlation between changes in BMD, trabecular bone micro-architecture, and bone strength documented in Objective 1 with changes in serum bone turnover markers

NCT ID: NCT02120053 Active, not recruiting - Alveolar Bone Loss Clinical Trials

Interest of Bone Substitute Material in Immediate Complete Denture

PANORAMIX
Start date: October 2013
Phase: Phase 2/Phase 3
Study type: Interventional

More than 2 million French people suffer from the widespread disability of edentulism, with large consequences on function, nutrition, aesthetics and well-being. Complete denture is a common therapeutic strategy. The immediate complete denture technique consists in placing the denture in the same clinical session as last anterior teeth extractions. With this technique, aesthetic and function are immediately reintroduced and the patient is never left toothless or without any denture. After teeth extractions, alveolar healing process leads to ridge resorption with bone volume modifications and reduction in height and width. However ridge bone volume is an essential factor in removable denture stability. With implantology as an alternative prosthetic strategy, ridge volume is also a most important factor to place dental implants in a situation close to previous dental roots position. In order to preserve bone volume, a current alternative strategy proposes to place bone substitute materials in tooth sockets after extraction. This strategy was never evaluated with the immediate complete denture technique. Hypothesis: A new strategy associating immediate complete denture and bone substitute material is more effective than conventional immediate complete denture in a bone preservation perspective.

NCT ID: NCT01892098 Completed - Osteoporosis Clinical Trials

Zinc and Bone Turnover Study in Adolescent Females

Start date: February 2007
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effects of zinc supplementation on bone growth over four weeks. Participants will agree to attend two visits to our laboratory and at each will complete blood and urine samples, questionnaires related to diet and physical activity and will receive a bone scan at the first appointment.

NCT ID: NCT01592539 Completed - Bone Clinical Trials

Skin Blood Flow in Patients With Type 1 Diabetes Mellitus Compared to Normal Controls

Start date: May 2012
Phase: N/A
Study type: Observational

The effects of high serum glucose on bone could be direct or could be indirect through its effects on the microvasculature. Previous studies by Rendell et al and Brugler et al have found significant differences in skin blood flow between diabetics and control. The investigators are proposing that blood flow measurements of the skin may be correlated with bone remodeling rates in iliac bone biopsies.