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Bone Resorption clinical trials

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NCT ID: NCT06374342 Recruiting - Bone Resorption Clinical Trials

BONE SUBSTITUTES OUTCOMES

Start date: September 16, 2021
Phase:
Study type: Observational

A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Bone Substitute range of products: CERAFORM, TRIHA+, NANOGEL, and all their private labels. TEKNIMED bone substitutes are legacy products, some marketed for more than 20 years. Their performance and safety have already been demonstrated by Post-Market Surveillance and previous clinical studies. The current Post-Market Clinical Follow-Up study aims to confirm these claims by collecting data in a "real-life" setting. The study is a retrospective and prospective global, single arm, non-controlled, multicentric, prospective observational study. Patients will be followed as per local standard medical care of the sites.

NCT ID: NCT06334159 Recruiting - Bone Resorption Clinical Trials

Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes

Start date: November 5, 2020
Phase: N/A
Study type: Interventional

The aim of this clinical trial is to compare the horizontal bone gain when grafting a bone substitute with non fixed resorbable collagen membranes (control group), versus fixed resorbable collagen membranes (test group) in resorbed ridges requiring Guided Bone Regeneration (GBR) to facilitate implant placement at 6 months.

NCT ID: NCT06324708 Recruiting - Clinical trials for Arthroplasty Complications

Analysis of Defined Elements on DXA in Patients Undergoing Hip Arthroplasty

THA_DXA
Start date: February 7, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the role of two-dimensional FEM models obtained from DXA images in the longitudinal assessment of periprosthetic bone, in subjects undergoing hip arthroplasty. Specifically, the study will focus on the joint analysis of changes in the parameters of bone mineral density (BMD) and Bone Strain Index (BSI) at the level of periprosthetic bone of the proximal femur in patients undergoing hip replacement surgery using DXA, evaluating the densitometric variation of these two parameters over time, starting from an immediately postoperative data and checking the change at 6 months to follow the patient through the postoperative course

NCT ID: NCT06206005 Recruiting - Bone Resorption Clinical Trials

Four Mandibular Implant-retained Overdentures in Individuals With Type 2 Diabetes

Start date: December 4, 2023
Phase:
Study type: Observational

Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking.

NCT ID: NCT06135506 Recruiting - Clinical trials for Alveolar Bone Resorption

Artificial Intelligence/Computer Guided Ridge Splitting for Treating Horizontal Ridge Defects

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

Aim of the current randomized clinical trial is to evaluate and compare the effectiveness of computer-guided ridge splitting approach assisted by artificial intelligence versus conventional approach combined with simultaneous implant Placement.

NCT ID: NCT05937035 Recruiting - Block Clinical Trials

Histological and Volumetric Evaluation of Customized Allograft Bone Blocks

Start date: May 25, 2024
Phase: N/A
Study type: Interventional

Customized bone blocks need CBCT and digital software to design the block needed to rehabilitate. Some advantages are reduced surgical time and better adaptation of the graft, leading to less complications. Objectives: The primary aim of this study is to determine the bone regeneration capacity through a histological study and the bone volumetric changes of allograft bone blocks in the posterior site of the mandible. The secondary outcome will be to assess the survival and success rate of dental implants placed in the allograft regenerated area. Materials and Methods: After studying the CBCT to regenerate the posterior sites of the mandible, the investigators will design CAD/CAM freeze- dried bone allograft to fit exactly on the defect morphology that the patients present. A full thickness flap will be released to have a correct access of the defects. The sterile blocks have to fit perfectly on the defect and fixed by screws. Covered with resorbable membranes fixed with pines and suture. 4 months later, 2nd CBCTwill be performed. During the implant surgery, a bone trephine will be removed and sent into a Laboratory to make a histological study of the bone block for histomorphometry. After 3 months, second-stage surgery and healing caps will be placed if needed. Impressions will be taken 2 weeks after to perform the final crowns.

NCT ID: NCT05910333 Recruiting - Bone Resorption Clinical Trials

Four Locator Attachment Mandibular Overdentures

Start date: March 28, 2023
Phase:
Study type: Observational

. There is little information on the degree of crestal bone loss around 4 inter-foraminal implant-retained mandibular overdentures (OVDs) and the amount of bone remodelling on the anterior maxilla and posterior mandibule on long-term function, particularly with different distributions.

NCT ID: NCT05902689 Recruiting - Clinical trials for Alveolar Bone Resorption

Application of Sticky Bone and Bio-Oss Collagen in Alveolar Ridge Preservation

Start date: May 31, 2023
Phase: N/A
Study type: Interventional

In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the control group underwent alveolar ridge preservation using Bio-Oss Collagen and the experimental group using Sticky Bone, to verify the application of Bio-Oss Collagen and Sticky Bone in alveolar ridge preservation

NCT ID: NCT05779345 Recruiting - Bone Resorption Clinical Trials

Stability of Short Implants Versus Standard Blx Implants With Internal Sinus Floor Elevation in Posterior Maxilla

Start date: March 2, 2023
Phase: N/A
Study type: Interventional

Implants in the maxillary posterior region are associated with compromised bone in both quantity - notably in vertical dimension- and quality. Along with the fact that the posterior teeth are subjected to higher occlusal forces than the anterior teeth (Marianne Morand & Tassos Irinakis, 2007). In order to overcome these shortcomings, various procedures have been advocated including open and closed sinus lift (Nkenke E & Stelzle F, 2009; Schropp et al, 2003). The use of short implants is a valid alternative for these procedures (Wallace SS & Froum SJ, 2003) sparing the need of applying augmentation techniques with the associated increased time, morbidity and complexity of such procedures.

NCT ID: NCT05772364 Recruiting - Orthopedic Disorder Clinical Trials

High- Versus Low-calcium Water for Bone Health

Start date: March 2, 2023
Phase: N/A
Study type: Interventional

The experimental study investigates which metabolic responses of calcium and parathyroid hormone are observable in blood and urine in a cohort of 41 healthy adults following a sequence of different exposures: low-calcium water first and high-calcium water afterward.