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Four Mandibular Implant-retained Overdentures in Individuals With Type 2 Diabetes

Bone Resorption Clinical Trial

Official title:
Clinical and Radiographic Outcomes Around Four Mandibular Implant-retained Overdentures in Individuals With Type 2 Diabetes: A Long-term Retrospective Preliminary Study

Clinical Trial Summary

Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking.

Clinical Trial Description

Chronic hyperglycemia is considered as a typical risk-factor that causes soft tissue inflammation and bone loss around natural teeth and implants. One possible explanation for this mechanism is that chronic hyperglycemia has the propensity to increase the levels of accumulated glycation end products (AGEs) in the serum and oral tissues that accelerates the production of proinflammatory cytokines that induce bone destruction around natural teeth and implants. However, it is relevant to indicate that dental implants in chronic hyperglycemia under ideal glycemic conditions can successfully osseointegrate and show predictable outcomes over long durations in both diabetic and non-diabetic patients. Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06206005
Study type Observational
Source Mansoura University
Contact Mohammed Elsawy, PhD
Phone 00201061314522
Email Dr_sawy@windowslive.com
Status Recruiting
Phase
Start date December 4, 2023
Completion date August 5, 2024
View Details
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