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Bone Neoplasm clinical trials

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NCT ID: NCT05881343 Completed - Clinical trials for Coronavirus Infection

Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery

COVID19&SURG
Start date: July 18, 2020
Phase:
Study type: Observational

Over the last months, the Rizzoli Orthopedic Institute in Bologna, Italy, has drained orthopedic urgencies from all other hospitals in the urban and suburban area. In this context urgencies are defined as fractures and primary or metastatic bone lesions with indication to non-deferrable surgery. A subset of these patients tested positive for SARS CoV 2, either before or after the surgical procedure. Anesthesiological clinical management of covid19 cases is complicated by the consequences of the viral infection on respiratory and cardio-vascular systems, renal function and coagulation. Similarly, management of asymptomatic patients is challenging because of the lack of data on possible specific complications. This study will report a snapshot of our early experience on perioperative clinical management of patients undergoing orthopedic surgery in the presence of SARS CoV 2 infection, ascertained or not at the time of surgery.

NCT ID: NCT04884048 Completed - Bone Neoplasm Clinical Trials

Multicentric Bone Tumor Imaging Report and Data System

BTI-RADS M
Start date: May 1, 2021
Phase:
Study type: Observational

In this study a previously described structured multimodality image report system for the characterization of focal bone lesions is evaluated in a larger patient population. The objective of this study is to evaluate the performance of this tool stratifying the malignancy risk of bone tumors.

NCT ID: NCT04310410 Completed - Pain Clinical Trials

Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis

PRE-FURTHER
Start date: April 11, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The PRE-FURTHER study aims to evaluate the feasibility of the combined treatment with radiotherapy and focussed ultrasound for pain palliation in patients with painful bone metastases, and to optimize the combined treatment logistics. Six to ten patients will be included according to in- and exclusion criteria.

NCT ID: NCT04074291 Completed - Quality of Life Clinical Trials

Cross Cultural Validation of the Italian Version of the Bt-DUX

Start date: August 20, 2019
Phase:
Study type: Observational

The purpose of the presented study is to translate the English Bt-DUX (Bt-DUX-Eng) questionnaire into the Italian language and then examine the validity of the Italian version of the Bt-DUX (Bt-DUX-It).

NCT ID: NCT03072186 Completed - Neoplasms Clinical Trials

Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery

ICG2
Start date: November 6, 2017
Phase: N/A
Study type: Interventional

This study is being done to demonstrate the feasibility of using a nasal endoscope to perform intraoperative angiography of surgical field, with the goals to evaluate anatomical landmarks and tumor characteristics during skull base surgery and publish a technical note.

NCT ID: NCT00841152 Completed - Bone Neoplasm Clinical Trials

Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute

BAGvsTCP
Start date: March 2009
Phase:
Study type: Observational

This study is designed to perform a head-to-head comparison of two synthetic ceramic bone graft substitutes, bioactive glass (BAG) and beta-tricalcium phosphate (TCP), in filling of contained bone defects following surgical evacuation of benign bone tumor or tumor-like conditions. Based on the investigators' previous preclinical research and an ongoing single-center randomized clinical trial on bioactive glass filling, the investigators expect BAG filling to be more efficient compared to TCP in promotion of defect healing and functional recovery after surgery.