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NCT04712123 Clinical Trial

Recurrent S. Aureus Infections in Osteoarticular Infections

Bone and Joint Infection Clinical Trial

— RELAPSTAPH  

Official title:
Recurrent S. Aureus Infections in Osteoarticular Infections

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04712123
Other study ID # 281
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date August 1, 2021
Est. completion date January 1, 2023

Study information
Verified date January 2022
Source Hospices Civils de Lyon
Contact Eugenie Mabrut, CRA
Phone 04 26 73 29 38
Email eugenie.mabrut@chu-lyon.fr
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Staphylococcus aureus osteoarticular infections, in particular those associated with the presence of implant, relapse in 20% of cases. Currently, the reasons for these relapses are poorly understood, whether on the microbiological or clinical side. The aim of this study is to improve knowledge on persistence of mechanisms of S. aureus

Recruitment information / eligibility
Status Recruiting
Enrollment 40
Est. completion date January 1, 2023
Est. primary completion date December 1, 2022
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - patients having had an osteoarticular infection with or without material due to S. aureus presenting a recurrence of S. aureus infection Exclusion Criteria: -

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• relapse due to S. aureus
to find out if it is the same S. aureus in both infections

Locations
Country Name City State
France Hospices Civils de Lyon Lyon

Sponsors (1)
Lead Sponsor Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary rate of patients having had an osteoarticular infection due to S. aureus proportion of patients having had an osteoarticular infection due to S. aureus between 2015 and 2020
Primary Description of patients having had an osteoarticular infection due to S. aureus type of patients: age, BMI, comorbidities... between 2015 and 2020
Primary Description of Bone and Joint Iinfection/Prosthesis Joint Infection implant or prosthesis or not, acute/ chronic, bacteriology between 2015 and 2020
Secondary rate of patients having had a relapse due to persistence of S. aureus proportion of patients having had an osteoarticular infection due persistence of S. aureus between 2015 and 2020
Secondary rate of S. aureus strain identical between the initial episode and the relapse proportion of relapse due to the same strain of S. aureus than in the initial episode between 2015 and 2020
See also
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