Lyon BJI Cohort Study

Status Recruiting

Clinical Trial Summary

The prospective Cohort includes all patients with bone or joint infection (BJI), with or without implant. The aim of this Cohort is to improve the knowledges about the treatment failure and the occurrence of serious adverse events. Various data of patients included are collected and will be analysed.

Patients with a bone or joint infection are treated at the department of infectious diseases, at Infectious disease department of Hospices Civils de Lyon. They have regularly a consultation with a physician: 2-3 weeks after surgery, 6 weeks after surgery, 3 months after surgery, 6 months after surgery, 12 months after surgery and 24 months after surgery. It allows to the physician to follow the evolution of the patient under treatment and after discontinuation of the treatment.

Several data are collected during the follow-up concerning: demographics data, treatment including the use of off-label antibiotics for the treatment of BJI, adverse events, microbiology, surgeries, healing or relapse, date of symptoms, ASA score, implant or not. If there is an implant, the date of implantation and the number of the prosthesis infected are collected.

This cohort allows to improve knowledge concerning the treatment failure and the occurrence of adverse events.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02817711
Study type	Observational
Source	Hospices Civils de Lyon
Contact	Eugénie Mabrut, ARC
Phone	(0)426732938
Email	eugenie.mabrut@chu-lyon.fr
Status	Recruiting
Phase	N/A
Start date	July 2002
Completion date	July 2022

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT05421312` - Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip	Phase 4
Active, not recruiting	`NCT04563325` - Oral-only Antibiotics for Bone and Joint Infections in Children	Phase 4
Completed	`NCT03627000` - Microbiological Epidemiology in Patients Experiencing Microbiological or Clinical Failure Following Reimplantation After a 2-stage Exchange Strategy for Hip or Knee Prosthetic Joint Infection
Completed	`NCT03311113` - Adherence to Oral Antibiotics In Patients With Osteoarticular Infections
Recruiting	`NCT05753215` - Controlled Trial of Omadacycline Randomized Treatment Given for Bone and Joint Infection	Phase 2
Completed	`NCT03209921` - Pharmacokinetic Variability of Daptomycin During Prolonged Therapy for Bone and Joint Infections	N/A
Completed	`NCT04418882` - Septic Management and Outcome of Open Fracture
Active, not recruiting	`NCT05248490` - Impact of Pharmaceutical Interviews Regarding the Management of Adverse Effects Related to the Antibiotic Therapy Used to Treat Osteoarticular Infections During Return Home	N/A
Completed	`NCT03624855` - Implant-Associated P. Aeruginosa Bone And Joint Infections : Experience In A Regional Reference Center In France
Recruiting	`NCT04496024` - Ofloxacin Concentration-toxicity Relationship in the Elderly	N/A
Recruiting	`NCT04933344` - Pharmacokinetics and Toxicodynamics of Daptomycin in Bone and Joint Infections
Recruiting	`NCT04538053` - BonE and Joint Infections - Simplifying Treatment in Children Trial	Phase 4
Completed	`NCT04373278` - Infection After Free Fibula Flap Reconstruction of the Mandible: a Retrospective Cohort Study
Completed	`NCT03209934` - Daptomycin > 6 mg/kg/Day as Salvage Therapy in Patients With Complex Bone and Joint Infection: Cohort Study in a Regionalreference Center	N/A
Recruiting	`NCT03611634` - Consitution Of A Biological Collection From Samples From The Gut Microbiote In Patients Having A Bone Or Joint Infection Treated By A Suppressive Subcutaneous Antibiotherapy With Betalactamine
Completed	`NCT03177369` - Teicoplanin-based Antimicrobial Therapy in Staphylococcus Aureus Bone and Joint Infection: Tolerance, Efficacy and Experience With Subcutaneous Administration	N/A
Recruiting	`NCT04722926` - Lyon PJI Retrospective Cohort Study
Completed	`NCT03852784` - Osteoarticular Infections With Pneumococcal
Recruiting	`NCT03796104` - Prognostic Impact of Delta-haemolysin Production Deficiency in Staphylococcus Aureus on the Prognosis of Infected Implant Treated by DAIR
Completed	`NCT03848104` - Evaluation of the Use of Cefoxitin in Combination in Continuous Parenteral Administration in the Treatment of Bone and Joint Infections