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Clinical Trial Summary

the aim of this study is to investigate the relationship between exposure to daptomycin and the occurrence of muscle toxicity or eosinophilic pneumonia in patients treated with daptomycin for bone and joint infection


Clinical Trial Description

Daptomycin is widely used in osteoarticular infections (IOA), as an alternative to vancomycin, and recommended for this use by various learned societies including the Infectious Diseases Society of America (IDSA) in 2013. Tolerance to daptomycin is generally favorable, with in particular better renal tolerance than vancomycin. However, two rare and potentially severe side effects have been described with this antibiotics: muscle toxicity and eosinophilic pneumonia. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04933344
Study type Observational
Source Hospices Civils de Lyon
Contact Tristan Ferry, Md,PhD
Phone 04 26 73 29 38
Email tristan.ferry@chu-lyon.fr
Status Recruiting
Phase
Start date June 15, 2021
Completion date July 1, 2022

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