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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03848104
Other study ID # 18-079
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2018
Est. completion date April 1, 2018

Study information

Verified date February 2019
Source Hospices Civils de Lyon
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Cephamycin related to 2nd generation cephalosporins, the use of cefoxitin has long been limited to antibiotic prophylaxis. Because of its spectrum (sensitive staphylococci, enterobacteria including ESBL, streptococci, anaerobes), its stability and its low cost, it could be useful in curative bone and joint infections, especially in case of infection polymicrobial disease in patients for whom antibiotic alternative per os is limited.


Recruitment information / eligibility

Status Completed
Enrollment 35
Est. completion date April 1, 2018
Est. primary completion date March 1, 2018
Accepts healthy volunteers
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria:

- patients havind had a bon and joint infeciton treated with cefoxitin in combination in continuous parenteral administration

Exclusion Criteria:

Study Design


Intervention

Other:
bone and joint infection treated with cefoxitin
the patients had cefoxitin in combination in continuous parenteral administration to treat their bone / joint infection

Locations

Country Name City State
France Hospices Civils de Lyon Lyon

Sponsors (1)

Lead Sponsor Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Rate of Treatment Failure Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
Secondary Rate of use of this strategy Descriptions of patients managed with this strategy Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
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