Nutrition Clinical Trial
Official title:
Efficacy of Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants
The purpose of this research study is to evaluate the effects (good and bad) of supplementation with Glutamine to that of a placebo (L-alanine), on your child and their Short Bowel Syndrome. Researchers are doing this study to see if the addition of Glutamine to oral/tube feeding (nutrition therapy) will work better by preventing bloodstream infections, improving growth, and/or changing the make-up of bacteria in your child's intestine. Glutamine is approved by the FDA for use in adults with Short Bowel Syndrome. In this study, the investigators will be assessing how well Glutamine affects Short Bowel Syndrome in children.
This is a double-blind, randomized placebo-controlled pilot study to investigate the efficacy of enteral glutamine (GLN) supplementation in 36 infants, ≤ 12 months of age with parenteral nutrition (PN)-dependent short bowel syndrome (SBS) due to massive small bowel resection for NEC and/or atresia on improving weaning of PN and preventing infections. The investigators intend to evaluate the effect of enteral feeding and GLN supplementation on the gut bacteria. The investigators will also recruit 12 age-matched controls to evaluate the normal gut bacteria. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT05934318 -
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
|
N/A | |
| Recruiting |
NCT05867433 -
Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments
|
N/A | |
| Completed |
NCT02376530 -
Price Changes and Nutrient Profiling Among Adult Grocery Shoppers
|
N/A | |
| Completed |
NCT01040975 -
Teen CHAT: Improving Physician Communication With Adolescents About Healthy Weight
|
N/A | |
| Completed |
NCT00957814 -
Nutritional Orientations and Adherence, Nutritional Status, Clinical and Life Quality Parameters of Heart Failure (HF) Patients
|
N/A | |
| Completed |
NCT00808756 -
Study on Fermentable Carbohydrates in Healthy Infants
|
N/A | |
| Completed |
NCT03290118 -
The Efficacy of Front-of-package Labelling Schemes: an Experimental Study
|
N/A | |
| Completed |
NCT03575884 -
Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers
|
N/A | |
| Completed |
NCT03963778 -
Organisational Culture and Nutritional Care
|
||
| Completed |
NCT05633251 -
Using Reinforcement Schedules to Increase Fruit&Vegetable Intake, Reduce Waste, and Increase School Lunch Participation
|
N/A | |
| Recruiting |
NCT05977959 -
Optimizing the Impact of the Healthy School Recognized Campus Program on Youth's CVD Risk Factors
|
N/A | |
| Recruiting |
NCT05138276 -
Effect of Autologous Cord Blood Mononuclear Cells for Digestive System in Preterm Neonates
|
Early Phase 1 | |
| Completed |
NCT03906851 -
Active and Healthy Kids in Telemark - a School Based Health Promoting Intervention
|
N/A | |
| Not yet recruiting |
NCT02950779 -
Assessment of Handgrip Strength in Adults With Inflammatory Bowel Disease
|
N/A | |
| Completed |
NCT02486588 -
Increasing Engagement With a Healthy Food Benefit
|
N/A | |
| Withdrawn |
NCT01184027 -
Impact of Nutrition and Swallowing Function of Head and Neck Cancer Patients During the Course of Treatment
|
N/A | |
| Completed |
NCT01178398 -
Understanding Fish Consumption Habits During Pregnancy
|
N/A | |
| Completed |
NCT01249508 -
Nutrition Labeling Program to Promote Healthy Dietary Patterns
|
N/A | |
| Terminated |
NCT00577499 -
Effect of Lubiprostone on Nutritional Status and Pulmonary Function in Adults With Cystic Fibrosis
|
N/A | |
| Completed |
NCT00109551 -
Community Trial of Zinc Supplementation on Preschool Child Mortality and Morbidity in Southern Nepal
|
Phase 3 |