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Blood Pressure clinical trials

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NCT ID: NCT03443596 Completed - Blood Pressure Clinical Trials

Blood Pressure Control in Acute Ischemic Stroke

BP-Stroke
Start date: December 1, 2014
Phase: Phase 2/Phase 3
Study type: Interventional

Management of acutely elevated blood pressure during the early phase of ischemic stroke remains controversial. In patients treated with IV-tPA, the risk of ICH is closely related to the BP levels. However, intensive reduction of BP carries a theoretical risk of clinical deterioration by inducing cerebral hypoperfusion. Assessment of cerebral perfusion before and after BP reduction is one of the most scientific method to evaluate the safety (and potential benefits) of BP management in the acute phase of stroke. This project will impact practices and delivery of BP management during the acute phase of ischemic stroke. The findings would aid in designing phase 3 clinical trials will track clinical indicators, including the impact on functional outcomes as well as quality-of-life and cost-effectiveness.

NCT ID: NCT03443375 Completed - Aging Clinical Trials

Exercise Periodization and Older Adults

Start date: January 2015
Phase: N/A
Study type: Interventional

The present study aimed at investigating the effects of two different resistance training protocols — nonperiodized (NP) and daily undulating periodization (DUP) — on hemodynamic, morphofunctional and cognitive parameters of robust older women. Methods: Forty-two older women were randomized allocated into one of the three experimental groups: NP, DUP, and control group (CG). Evaluations of the hemodynamic, morphofunctional and cognitive parameters occurred before, during and after six months. The exercise groups performed the program of exercise twice a week over 22 weeks. In NP, the two weekly sessions were based on 3 sets of 8-10 repetitions at a difficult intensity. However, in DUP, a power exercise session based on 3 sets of 8-10 repetitions at a moderate intensity was added in the first session of the week.

NCT ID: NCT03442907 Completed - Blood Pressure Clinical Trials

Personalized Blood Pressure Management

IMPROVE
Start date: March 1, 2018
Phase: N/A
Study type: Interventional

The aim of this research project is to find out whether a personalized definition of the lower blood pressure threshold based on the individual blood pressure profile by means of preoperative 24-hour blood pressure measurement can reduce organ damage (brain, kidney, heart) through reduced blood flow during surgery.

NCT ID: NCT03433963 Completed - Blood Pressure Clinical Trials

The Use of L-arginine to Mitigate the Cardiovascular Effects of Exposure to Traffic-related Air Pollution

Start date: January 2, 2018
Phase: N/A
Study type: Interventional

The present study is aimed to investigate whether oral L-arginine supplementation reduces the adverse cardiovascular effects of exposure to traffic-related air pollution among a group of non-smoking adults with elevated blood pressure.

NCT ID: NCT03426774 Completed - Physical Activity Clinical Trials

Simulated Passive Jogging & Jumping Devices & NO

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Movement is important for overall health. Lack of movement has been shown to be associated with numerous diseases. This study will assess the validity and usefulness of two innovative low risk, non-invasive wellness devices, the Gentle Jogger® and the Gentle Jumper that passively simulate the physical activities of jogging and jumping, respectively. The study will evaluate whether or not each of the devices in different body postures (seated, lying down, slight recumbent and slight head down) produces changes in blood pressure, and indices of dilatation of blood vessels, in a younger (25-59yr) and older (> 60 yrs.) subject population. Volunteers will be paid for their participation in the study. A substudy of this larger study ( Effects of Gentle Jogger on blood pressure), will determine the effects of 30 min of gentle jogger in seated and supine posture compared to Sham

NCT ID: NCT03410342 Completed - Blood Pressure Clinical Trials

The Effects of Types of Fruits and Vegetables on Vascular Function

CIRCUS
Start date: September 4, 2017
Phase: N/A
Study type: Interventional

The CIRCUS study is a randomised controlled, cross-over trial to evaluate the effects of increased intakes of citrus fruits and cruciferous vegetables on vascular function in 36 untreated, prehypertensive participants.

NCT ID: NCT03404999 Completed - Hypertension Clinical Trials

Clinical-Decision Support to Improve Hypertension Care in Primary Care

Start date: July 19, 2017
Phase: N/A
Study type: Interventional

Approaches are needed to help primary-care pediatricians address high blood pressure. This study will test whether an electronic health-record-based tool to address high blood pressure is feasible and improves the evaluation and management of high blood pressure in clinical practice. If successful, this approach can be used to address other lifestyle-related and complex health problems (e.g., dyslipidemia and diabetes), then disseminated and used nationwide. The investigators have developed a new, electronic health-record (EHR)-based tool that is designed to help pediatricians: 1. IDENTIFY AND DOCUMENT 1. when a child's blood pressure is elevated, and 2. whether it has been elevated before--including number of prior elevations to document the correct diagnosis (for example, elevated blood pressure, vs. hypertension stage 1, vs. hypertension stage 2), THEN 2. ORDER the next action(s) needed per guideline-based recommendations, AND per prior actions taken--including: 1. laboratories and studies per 2017 updated guidelines 2. follow-up interval in primary care 3. referral to nephrology, when indicated, and 4. patient education on diet/lifestyle modification. The investigators are working on improving this system further with addition of orders for: 1. referral for sleep-apnea testing and treatment, when indicated, and 2. blood-pressure medications (for example, initiation, titration, or addition of agents depending on blood-pressure control, comorbid conditions [e.g., diabetes], and risk for pregnancy)

NCT ID: NCT03403166 Completed - Blood Pressure Clinical Trials

Metabolomics of the Dietary Approaches to Stop Hypertension (DASH) Dietary Pattern

Start date: August 1993
Phase: N/A
Study type: Observational

The present record represents a secondary data analysis of the Dietary Approaches to Stop Hypertension (DASH) trial. Study data and specimens were accessed through the National Heart, Lung, and Blood Institute (NHLBI) Biologic Specimen and Data Repository Coordinating Center (BioLINCC). A global, untargeted, metabolomic profile was used to investigate biomarkers of the DASH dietary pattern as well as blood pressure change.

NCT ID: NCT03401489 Completed - Hypertension Clinical Trials

PACESETTER: Program to Avoid Cerebrovascular Events Through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor

Start date: July 14, 2020
Phase: N/A
Study type: Interventional

Program to Avoid Cerebrovascular Events through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor (PACESETTER) aims to assess the incorporation of its stroke intervention into 2 safety net/academic health sytems in a given US state especially burdened by stroke, thereby enhancing knowledge about the complexity of stroke interventions, and especially the nature of the challenges encountered in low resource settings and for populations traditionally underrepresented in research. Altogether, the intervention, if proven implementable and effective, may eventually be exported to other medically underserved populations in the US beyond SC as a feasible model of post-stroke management.

NCT ID: NCT03382691 Completed - Blood Pressure Clinical Trials

Accuracy of a Blood Pressure Measuring Mobile Device in Volunteers

Start date: December 2016
Phase: N/A
Study type: Interventional

The accuracy and safety of blood pressure module of new mobile device (M- HEALTHCARE device) is evaluated according to Korean FDA guidelines in 100 healthy volunteers.