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Blood Pressure clinical trials

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NCT ID: NCT01755312 Terminated - Blood Pressure Clinical Trials

The Effect of Medication Reminder Technology on Medication Adherence and Hypertension Outcomes

Start date: June 2013
Phase: N/A
Study type: Interventional

This study to evaluates how a med reminder affects the patient's ability to take medications as prescribed

NCT ID: NCT01705080 Terminated - Hypertension Clinical Trials

IntErnational Long-term Follow-up Study of Patients With Uncontrolled HyperTensioN

EnligHTN-II
Start date: January 17, 2013
Phase:
Study type: Observational

The purpose of this post market clinical investigation is to further evaluate the safety and performance of the EnligHTN™ Renal Denervation System in the treatment of patients with uncontrolled hypertension.

NCT ID: NCT01701622 Terminated - Blood Pressure Clinical Trials

The Blood Pressure Effects of Febuxostat in Patients Previously Treated With Allopurinol: A Pilot Study

Start date: January 2010
Phase: N/A
Study type: Interventional

Hyperuricemia (high uric acid level) has been correlated to hypertension (high blood pressure) and overall cardiovascular disease risk in several studies. The relationship has even been noted to be independent of metabolic syndrome and kidney function. It has been repeatedly noted that hyperuricemia was an independent risk factor of death in those at high cardiovascular disease risk. A recent review concluded that there is strong evidence that hyperuricemia and gout are coupled with atherosclerosis and cardiovascular events. Although this correlation of hypertension and hyperuricemia is known, there has only been one published study that has evaluated if lowering the uric acid would reduce the blood pressure. The authors concluded that in newly diagnosed hypertensive adolescents, allopurinol decreased the blood pressure. Despite this, further evaluation of this therapeutic approach has not been studied. The hypothesis of this study is that febuxostat, a new xanthine oxidase inhibitor, has blood pressure lowering effects superior to allopurinol in patients diagnosed with gout.

NCT ID: NCT01633814 Terminated - Aging Clinical Trials

Hormone Replacement and Neural Cardiovascular Control in Postmenopausal Women

Start date: September 2011
Phase: N/A
Study type: Interventional

Older women have an exaggerated increase in blood pressure during exercise. However, the reasons for this are unclear. It is important to investigate this phenomenon because a greater blood pressure response to exercise has been associated with an increased risk of stroke and mortality in otherwise healthy individuals. A unique aspect of aging in women is the profound change in hormone levels (i.e. estrogen and progesterone) associated with menopause. The influence of changes in estrogen and progesterone levels on the cardiovascular responses to exercise is poorly understood. However, it has been suggested that these hormones might change the responsiveness of the cardiovascular system. Possible mechanisms that could account for these changes are the arterial baroreflex and feedback from the exercising muscle (known as the exercise pressor reflex), both of which are known to powerfully modulate blood pressure during exercise. However, to date, few human studies have thoroughly examined the influence of changes in hormone levels on baroreflex function during exercise or the exercise pressor reflex in older women. As such, the purpose of this research project is to assess baroreflex function and the exercise pressor reflex in older women after transdermal estrogen alone, transdermal estrogen plus progesterone, progesterone alone and placebo.

NCT ID: NCT01482325 Terminated - Clinical trials for Blood Pressure (Low, Normal, High)

SuperSTAT 2.0 Noninvasive Blood Pressure Algorithm Enhancement

SNIPE
Start date: November 2011
Phase: N/A
Study type: Interventional

The primary objective of this study is to show that the noninvasive blood pressure software algorithm meets engineering requirements.

NCT ID: NCT01461330 Terminated - Blood Pressure Clinical Trials

Lifestyle Changes in Patients With Type 2 Diabetes Mellitus and Hypertension

Start date: February 2011
Phase: N/A
Study type: Interventional

Data obtained in hypertensive patients without diabetes suggest that increased association of non-pharmacological treatment in patients with diabetes and hypertension may be associated with an improvement in blood pressure control. Despite the beneficial results found, is not yet known the magnitude of the effect of a DASH diet associated with the stimulus of physical activity on BP in patients with type 2 diabetes. The beneficial effects on blood pressure of an additional non-pharmacological intervention to drug therapy may have an even greater impact in patients with treatment-resistant hypertension The aim of this study is to evaluate the effect of changes in lifestyle on blood pressure in patients with type 2 diabetes and hypertension resistant to treatment.

NCT ID: NCT00224939 Terminated - Blood Pressure Clinical Trials

Pre-ESRD Syndrome in High Risk African Americans

Start date: July 2002
Phase: N/A
Study type: Interventional

Evaluation of the dipping status of blood pressure (wether blood pressure decreases at night) and renal functional reserve and wether non-dippers (those whose blood pressure does not decrease at night) can be modulated to dippers with potassium treatment.