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Bleeding clinical trials

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NCT ID: NCT02872649 Terminated - Bleeding Clinical Trials

Dabigatran as an Alternative Anticoagulant in Patients With Left Ventricular Assist Device (LVAD)

Start date: January 2013
Phase: Phase 2
Study type: Interventional

Patients with severe heart failure supported by left ventricular assist device (LVAD) require adequate long-term anticoagulant therapy. New oral anticoagulants such as the direct thrombin inhibitor dabigatran may represent an alternative to Coumarin for long-term anticoagulation. In this pilot single-center study, thirty LVAD patients with stable renal function were scheduled to receive phenprocoumon or dabigatran for long-term anticoagulation after implantation of a HeartWare HVAD system following an open-label balanced parallel group design.

NCT ID: NCT02851940 Withdrawn - Pain Clinical Trials

Pain and Bleeding Following Hypertonic Saline Sclerotherapy Compared to Brand Ligation for Symptomatic Hemorrhoids

Start date: September 2016
Phase: N/A
Study type: Interventional

The investigators aim at prospectively comparing procedural pain, adverse events and rebleeding rates of anoscopic rubber band ligation and endoscopic hypertonic saline injection in patients with symptomatic hemorrhoidal disease

NCT ID: NCT02849691 Completed - Bleeding Clinical Trials

Plasma Dipeptidyl-peptidase-4 Activities With No-reflow and Bleeding

Start date: January 2014
Phase: N/A
Study type: Observational

Dipeptidyl-peptidase-4 (DPP4) is an important regulator of incretins and inflammation, and participates in the pathophysiological process of acute myocardial infarction (AMI). However clinical data of DPP4a in AMI patients is sparse. This study was to investigate the role of plasma DPP4 activity (DPP4a) in patients with ST-segment elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI). This was a analysis of consecutive patients conducted at a tertiary referral center from January 2014 to October 2015. The investigators included 747 STEMI-patients, treated with PCI from January 2013 to October 2015. Blood samples were collected immediately at admission. The patients were divided into four groups according to DPP4a quartile.

NCT ID: NCT02806102 Recruiting - Clinical trials for Acute Myocardial Infarction

CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction II (COREA-AMI II)

Start date: January 2004
Phase: N/A
Study type: Observational [Patient Registry]

This study is intended to provide contemporary data on the residual cardiovascular risk in all consecutive patients with acute myocardial infarction, especially in patients who survived stably within one-year after percutaneous coronary intervention. In addition, this study will identify which baseline clinical, angiographic, or treatment factors are associated with residual cardiovascular risk and bleeding events

NCT ID: NCT02785575 Active, not recruiting - Cardiac Surgery Clinical Trials

Adjusted Calculation of Heparin and Protamin Dosing and Correlation With Postoperative Bleeding and Transfusions

Start date: April 2016
Phase: Phase 4
Study type: Interventional

The study will compare a novel calculation model (HeProCalc AB) with a standard weight-based and activated clotting time adjusted calculation for the dosing of Heparin and protamine and assess the impact on postoperative bleeding and blood transfusions after cardiac surgery.

NCT ID: NCT02722720 Completed - Stroke Clinical Trials

Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral

Start date: September 2015
Phase: N/A
Study type: Interventional

The aim is to compare the safety of using transfemoral and transradial approach in patient undergoing carotid arteries stenting.

NCT ID: NCT02694341 Withdrawn - Bleeding Clinical Trials

Bakri Balloon in Placenta Previa

BB-ATS
Start date: December 2018
Phase: N/A
Study type: Interventional

The Bakri intrauterine balloon can achieve haemostasis in cases of postpartum haemorrhage, including haemorrhage associated with placenta previa by compressing the lower uterine segment.

NCT ID: NCT02677818 Withdrawn - Ischemic Stroke Clinical Trials

The Relationship Between Clotting Factor VIII and Bleeding Adverse Reactions in Patients Under the Therapies of Thrombolysis, Anticoagulation and Anti-platelet

Start date: May 2016
Phase:
Study type: Observational

The purpose of this study is to determine whether Plasma Factor VIII Levels are related to the treatment of bleeding in ischemic stroke(IS).

NCT ID: NCT02655653 Completed - Bleeding Clinical Trials

Efficacy of Tranexamic Acid and Epsilon-aminocaproic Acid in Reducing Bleeding and Transfusions in Cardiac Surgery

Start date: October 2008
Phase: Phase 3
Study type: Interventional

The investigators primary objective is to compare the effectiveness of epsilon-aminocaproic acid (EACA) and tranexamic acid (TA) in reducing bleeding and transfusion in cardiac surgery, with the hypothesis that TA is more effective. The investigators also seek to further examine the clinical benefits and adverse effects profiles of epsilon-aminocaproic acid and tranexamic acid.

NCT ID: NCT02640794 Completed - Stroke Clinical Trials

Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVI

ARTE
Start date: January 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare aspirin/acetylsalicylic acid+ clopidogrel with aspirin/acetylsalicylic acid alone as antithrombotic treatment following TAVI for the prevention of major ischemic events (MI, ischemic stroke) or death without increasing the risk of major bleeding events.