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Behavior clinical trials

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NCT ID: NCT05516264 Active, not recruiting - Behavior Clinical Trials

Behavioural and Physiological Responses to Dog Visits in Nursing Homes

Start date: September 5, 2022
Phase: N/A
Study type: Interventional

In brief the study aims to investigate how nursing home residents receiving dog visits respond to contact with the dog, by comparing visits with and without a dog present. The investigators will measure the response with non-invasive measures of the immediate physiological response, and objective behavioural measurements to quantity the activity and the actual amount and intensity of contact to the dog.

NCT ID: NCT05493072 Completed - Behavior Clinical Trials

RxConnect User Testing Study

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

Background Medication errors are the leading cause of preventable harm in healthcare settings worldwide. An estimated 237 million medication errors occur in England alone every year, with 66 million considered clinically significant. There is an estimated cost to the NHS from definitely avoidable adverse drug reactions as a result of these errors of £98.5 million per year, consuming 181,626 bed-days and causing to 712 deaths. Medication related clinical decision support systems, often integrated with electronic prescribing systems, are rapidly increasing in number over the last few decades, ranging from drug-drug interaction alerts to allergy checks and formulary support. A recent systematic review summarised that these systems are still relatively immature, with limited use of patient-specific input or human factors research used to develop them. There is an opportunity to improve these systems significantly for the benefit of the user and for patient safety. The World Health Organization propose that interventions to reduce medication error should include the development of technologies that are well understood and designed for the systems and practice they are applied to. Human factors and usability engineering is an integral part of developing medical devices, such as clinical decision support (CDS) systems, to ensure that such devices are easy to use and can be used safely as intended. User testing / usability testing, which may incorporate several methods, should be conductive throughout the development process (at formative, summative assessment, and during post-market surveillance). These methods are now becoming more common place in healthcare technology research and should continue to support the development of new technologies. RxConnect RxConnect, a newly registered UKCA marked medical device, is an on-demand clinical decision support tool that receives medication and patient inputs and uses them to filter an underlying formulary, such as the BNF, and perform dosing calculations, as needed, to return patient-specific dosing recommendations. RxConnect does not have a user interface and relies on an integration with third-party systems, such as electronic prescribing systems, to deliver CDS services to clinical end users. For this study a prototype user interface for RxConnect that emulates a typical electronic prescribing system will be used. The study team hypothesise that use of RxConnect as a digital prescribing aid is quicker, easier, and as safe to use as currently available prescribing aids. This study aims to utilise user testing to prove or disprove the above hypothesis and to generate quantitative and qualitative outputs to support the continued development of RxConnect prior to clinical deployment.

NCT ID: NCT05405400 Completed - Depression Clinical Trials

The Sugira Muryango Longitudinal & Spillover Study

Start date: April 20, 2022
Phase:
Study type: Observational

The Early Childhood version of Sugira Muryango is a family-based, home-visiting intervention targeted at early childhood development and implemented with families living in extreme poverty in three districts of Rwanda. This version of Sugira Muryango was first tested in two small pilot studies and a large cluster randomized trial (CRT) was implemented between February 2018 and September 2019 . Pre- to post-intervention findings demonstrated that Sugira Muryango led to improvements in caregiver behaviors linked to child development and health as well as reductions in violence, which were sustained 12 months after the intervention, at which time improvements in child development were observed. The Research Program on Children and Adversity in the Boston College School of Social Work is led by Dr. Theresa S. Betancourt and will, in partnership with the University of Rwanda, FXB-Rwanda and Laterite, conduct a longitudinal follow-up study to investigate the longer-term outcomes of the Sugira Muryango intervention in families who participated in the CRT. The four-year follow-up will examine the long-term and sustained outcomes of the intervention. In particular, the investigators will look at key indicators of long-term positive outcomes for children such as school readiness and transition to formal schooling. Given the lack of longitudinal research on intervention programs supporting ECD in sub-Saharan Africa, this study will contribute greatly to the body of knowledge on the costs and benefits of investments in ECD and guide policy makers and government leaders on making impactful investments in children, leading to long-term benefits for the population at large. The follow-up study involves two activities: Activity A: Pilot to assess measures performance of newly added measures and field test study protocols. Activity B: Four-year follow-up of families who participated in the CRT of the Sugira Muryango intervention.

NCT ID: NCT05400837 Recruiting - Atrial Fibrillation Clinical Trials

Patient Centered Mobile Health Technology Enabled Atrial Fibrillation Management

mTECHAFib
Start date: June 26, 2023
Phase: N/A
Study type: Interventional

The overall objective of this proposal is to evaluate the feasibility of a comprehensive digital atrial fibrillation (AFib) management tool that will empower patients to a) take an active role in learning about AFib management options, starting and adhering to evidence-based therapies and lifestyle changes and b) to guide the patients during AFib episodes which are associated with anxiety and impairment in quality of life. Researchers plan to evaluate the feasibility and preliminary efficacy of this novel digital toolkit in improving quality of life and decreasing AFib burden in a pilot randomized clinical trial (RCT).

NCT ID: NCT05385484 Active, not recruiting - Clinical trials for Human Immunodeficiency Virus

A Savings Intervention to Reduce Men's Engagement in HIV Risk Behaviors

Start date: July 18, 2022
Phase: N/A
Study type: Interventional

This randomized control trial will test an economic intervention to reduce Kenyan men's engagement in behaviors that increase the risk of HIV/STIs. Participants randomized to the intervention group will be able to open accounts with a partner bank and will be incentivized to save with lottery-based rewards.

NCT ID: NCT05352308 Not yet recruiting - Behavior Clinical Trials

Evaluation of a Narrative Communication Intervention to Increase Human Papillomavirus Vaccination Intentions and Uptake

Start date: April 20, 2022
Phase: N/A
Study type: Interventional

The current study aims to evaluate a newly developed CSM narrative intervention in increasing HPV vaccination intentions and uptake in adults aged 18 to 26 years. The efficacy of the newly designed CSM-guided narrative video will be compared against a time and attention video and the standard of care print educational materials in increasing the intentions and uptake of the HPV vaccine in an adult Hispanic-majority college population. It is expected that participants receiving the CSM-guided narrative video will have greater HPV vaccine intentions compared with participants in the time and attention video and standard of care print education material groups. It is also hypothesized that participants receiving the CSM-guided narrative video will have greater HPV vaccine uptake at one month post-intervention compared with participants in the time and attention video and standard of care print education material groups.

NCT ID: NCT05339737 Not yet recruiting - Critical Illness Clinical Trials

The Nociception Level (NOL) Index for Pain Assessment in the Adult Intensive Care Unit

NOL-ICU
Start date: May 1, 2022
Phase:
Study type: Observational

Assessing pain in the adult intensive care unit (ICU) is challenging because many patients are unable to communicate due to mechanical ventilation and sedation. Therefore, it is necessary to have alternative methods to assess pain in this vulnerable patient population. In this project, the use of a multi-parameter technology (i.e., the Nociception Level (NOL) index) will be tested for pain assessment in ICU adults. The NOL index is a value from 0 to 100 obtained by calculating different parameters (e.g., pulse, skin temperature) captured through a small probe placed on the patient's finger. The NOL was initially developed for assessing nociception, pain and analgesia in anesthetized patients undergoing surgery, and its use in the ICU is new. The NOL's use before, during and after standard care procedures known to be painful (e.g., tube or drain removal, suctioning of secretions through the endotracheal tube) and non-painful (e.g., cuff inflation to measure blood pressure, soft touch) in ICU adults. The NOL will be monitored in three groups: a) patients able to communicate so they can self-report their pain (gold standard criterion) and express behaviors, b) patients unable to communicate but express behaviors (reference criterion), and c) patients unable to communicate and to express behaviors. In the first group, patients will be asked to self-report their pain and procedural distress on a 0 to 10 scale. In the first and second group, patients will be assessed for pain using a standardized behavioral scale which will be completed by trained research staff. In the third group, only the NOL will be monitored. Analgesic and sedative medication administered to patients will also be documented from medical charts. The ability of the NOL to detect pain based on self-reports of pain and behavioral scores, and its ability to discriminate between painful and non-painful procedures will be examined. If found to be useful, the NOL could be used as an alternative measure of pain and improve its recognition and treatment in vulnerable ICU patients.

NCT ID: NCT05335616 Completed - Behavior Clinical Trials

Behavioral Change Simulation Experiment Regarding Dentists' Repair Behavior

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The aim of the present study is to determine the effect of two potential interventions on dentists' behavior regarding the repair of partially defective dental restorations.

NCT ID: NCT05319821 Enrolling by invitation - Physical Activity Clinical Trials

PA Moves Trial - PCP Participants

Start date: September 21, 2022
Phase: N/A
Study type: Interventional

The purpose of this voluntary research study is to determine the impact of an ECHO intervention on the likelihood that rural primary care providers (PCP) will refer their physically inactive patients to be more active.

NCT ID: NCT05310682 Active, not recruiting - Behavior Clinical Trials

Data-Informed Platform for Health (DIPH)

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The overall aim of the Data-Informed Platform for Health (DIPH) is to improve Maternal, Newborn and Child Health (MNCH) programmes and services at the district level. The DIPH strategy does this by bringing together data on inputs and processes to promote the use of local data for decision-making, priority-setting, and planning by introducing a structured decision-making process at the district level. The DIPH is embedded in the existing district decision-making forum- e.g., performance review teams meetings - adding a structured coordination process between different departments and formal data-sharing for evidence-based decision-making, planning, and resource allocation according to local health priorities. Conceptually, the DIPH strategy uses a structured set of processes involving five pre-defined steps and standardised job-aids corresponding to each step to facilitate linking data from health and associated departments and stakeholders. A typical DIPH cycle has five steps around a health theme, which take about four months to complete. Technical assistance is provided by the district stakeholders' induction, orientation, and handholding during the implementation of the initial cycles. The DIPH job-aids - a set of standardised job-aids (paper forms or web-based interface) - are designed to help organise and interpret data from multiple sectors involved in delivering services around the chosen theme using a common data-sharing platform. They are aimed at district leadership and management teams systematically using, inputting and processing data for decision-making, planning and progress monitoring of the theme. In Ethiopia, the DIPH intervention research will be employed for four cycles in the North Shoa zone (12 intervention and 12 comparison districts), coupled with process evaluation to understand and improve ongoing implementation issues. In addition, for the impact evaluation of DIPH implementation, a before-and-after comparison of the study outcomes between intervention and comparison study arms will be carried out via district health administration surveys. This study is a collaboration between the Ethiopian Public Health Institute (EPHI) and the London School of Hygiene and Tropical Medicine (LSHTM).