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Atrial Fibrillation clinical trials

View clinical trials related to Atrial Fibrillation.

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NCT ID: NCT06187155 Recruiting - Clinical trials for Atrial Fibrillation and Flutter

Impact of Education Level on Clinical Outcomes in Self-INR Managed Patients

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Oral anticoagulation (OAC) is indicated in a wide variety of clinical conditions including atrial fibrillation (AF), mechanical valve prosthesis (MVP), deep vein thrombosis and pulmonary embolism. Although direct OAC has replaced vitamin K antagonists (VKA) in non-valvular AF due to lower bleeding risk, it's still recommended to use VKA specifically in cases of valvular AF, MVP and anti-phospholipid syndrome. VKA has a narrow therapeutic range and multiple drug interactions causing unpredicted pharmacodynamics. This requires regular monitoring of the international normalized ratio (INR) level to ensure it's in the target therapeutic range and prevent extreme values that may result in thrombo-embolic events or sometimes fatal bleeding. Self-INR monitoring and management have emerged recently as a safe cost-effective alternative to standard management, with evidence of tighter control of INR, reduction of thrombo-embolic events, and improving treatment-related quality of life. However, there are no specific criteria for patient selection. Whether the level of education and other social factors would affect the outcomes of self-management is still not clear. Owing to the wide geographical area served by Aswan Heart Center, many patients have to cover long distances to follow up their INR and seek medical advice regarding adequate dose modification. This may result in reluctance and non-compliance to clinic visits and INR testing. Proper education, training and providing an alternative near place to measure the INR and self-adjust warfarin dose is expected to improve patient adherence and compliance.

NCT ID: NCT06183879 Recruiting - Atrial Fibrillation Clinical Trials

Comparison of Expandable and Fixed Size Cryoballoon for the Treatment of Paroxysmal Atrial Fibrillation

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare two different, market approved, cryoballoon devices for the treatment of paroxysmal atrial fibrillation (AF). The main aims of the study are: - to compare the efficacy of two ablation devices (acute and 1 year success rates) - to compare the procedural characteristics (procedure duration, fluoroscopy duration, ablation time - to compare the complication rates Participants who have indication for cryoballoon ablation of AF will be randomized in 1:1 fashion to older fixed size cryoballoon and newer expandable cryoballoon. Standard of care cryoballoon procedure will be performed alongside with standard postprocedural follow-up. • to compare the complication rates Participants who have indication for cryoballoon ablation of AF will be randomized in 1:1 fashion to older fixed size cryoballoon and newer expandable cryoballoon.

NCT ID: NCT06176131 Recruiting - Atrial Fibrillation Clinical Trials

The Cardio-share Telemedicine Cross-sector Collaboration Model for Managing Vulnerable Patients With Heart Failure

ADHFQUAL-BFH
Start date: January 1, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to explore the potential of implementing a telemedicine-based cross-sector collaboration model to manage patients with frequent admissions with decompensated heart failure. The main question(s) it aims to answer are: - Characterization of conditions that make these patients vulnerable - Description of key-elements that makes possible to manage the patients with the cardio-share model Participants are: - Patients - will be helped to use the available telemedicine tools - General Practitioners - will be offered teleconferences with cardiologists (chat and video) on demand - Community health workers (caregivers at the patient home or in elderly home) - will be guided to assist the patients to use the available telemedicine tools Researchers will compare readmission rates (primary outcome) and quality of life of patients where the cardio-share management model is successfully implemented one year before and after the implementation.

NCT ID: NCT06175234 Recruiting - Atrial Fibrillation Clinical Trials

Feasibility Study on the FARAVIEW Technology

NAVIGATE PF
Start date: April 3, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to gather data regarding the utilization of the FARAVIEW™ feature of the RHYTHMIA HDx Mapping System when used in conjunction with the FARAWAVE NAV Pulsed Field Ablation catheter in subjects undergoing catheter-based endocardial mapping and catheter-based ablation treatment of Atrial Fibrillation.

NCT ID: NCT06174506 Recruiting - Atrial Fibrillation Clinical Trials

The Role of hs Troponin I and NT-proBNP in Predicting Atrial Fibrillation in Patients With Permanent Pacemakers

Start date: December 1, 2023
Phase:
Study type: Observational

The goal of this clinical trial is to answer the research question whether hs Troponin I and NT-proBNP have a role in detecting atrial fibrillation in patients with pacemakers. Objectives of the study: 1. To survey some risk factors for atrial fibrillation in patients with permanent pacemakers. 2. To determine the role of hs Troponin I and NT-proBNP in predicting new-onset atrial fibrillation within follow-up time. 3. To build a model to predict the prognosis of atrial fibrillation based on the detected subclinical markers related to atrial fibrillation and classic cardiovascular risk factors.

NCT ID: NCT06172699 Recruiting - Cardiac Arrhythmia Clinical Trials

Assert-IQ Implantable Cardiac Monitor (ICM) Post Market Study

Assert-IQ
Start date: January 1, 2024
Phase:
Study type: Observational

This is a prospective, non-randomized, multi-center, real-world post-market study to collect and evaluate data regarding the performance of the enhanced atrial fibrillation detection algorithm of the Assert-IQTM Implantable Cardiac Monitor (ICM) device.

NCT ID: NCT06170606 Recruiting - Clinical trials for Paroxysmal Atrial Fibrillation

POLARx Post Approval Study (POLARx PAS)

Start date: June 2024
Phase: N/A
Study type: Interventional

To collect clinical data on safety, effectiveness and procedural success of Boston Scientific's Cardiac Cryoablation System (includes all BSC commercially available POLARx/POLARx Fit catheters) when used to perform pulmonary vein isolation (PVI) in the ablation treatment of de novo Atrial Fibrillation (AF).

NCT ID: NCT06167434 Recruiting - Atrial Fibrillation Clinical Trials

Future Cardia™ Insertable Cardiac Monitor in Subjects With Paroxysmal Atrial Fibrillation (First-in-Human Study)

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

This study is a first-in-human, prospective, multi-center, pre-market single-arm clinical trial to evaluate the Future Cardia™ ICM.

NCT ID: NCT06160076 Recruiting - Atrial Fibrillation Clinical Trials

Inflammatory Response Following " Pulsed Field Ablation " vs. Radiofrequency Ablation-2

RIPAF-2
Start date: October 16, 2023
Phase:
Study type: Observational

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Catheter ablation using pulmonary vein isolation (PVI) in an established treatment strategy for AF. Pulsed Field Ablation (PFA) is a non-thermal ablation modality which has recently been introduced in clinical practice with the aim of improving PVI efficacy and safety. The aim of this study is to analyse whether PFA generates a lower inflammatory reaction as compared to conventional radiofrequency ablation (RFA).

NCT ID: NCT06159985 Recruiting - Clinical trials for Coronary Artery Disease

Effect of Left Posterior Pericardiotomy for the Prevention of POAF

ELIMINATE-AF
Start date: December 11, 2023
Phase: N/A
Study type: Interventional

This study is planned to evaluate the effect of left posterior pericardiotomy for the prevention of postoperative atrial fibrillation after coronary artery bypass grafting. Eligible patients will be randomized to be created or not to be created the left posterior pericardiotomy at the end of the operation, and the incidence of postoperative atrial fibrillation will be compared.